Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling. - Wikidata - wikimedia - TriplyDB

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

http://www.wikidata.org/entity/Q37480767

about

A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes Comparative study of tumorigenesis and tumor immunity in invertebrates and nonmammalian vertebrates Drosophila as a model for context-dependent tumorigenesis.Modeling tumor invasion and metastasis in Drosophila Evaluation of Lethal Giant Larvae as a Schistosomiasis Vaccine Candidate.Lethal (2) giant larvae: an indispensable regulator of cell polarity and cancer development.Occluding junctions of invertebrate epithelia.Hugl-1 inhibits glioma cell growth in intracranial model.Distribution of lethal giant larvae (Lgl) protein in the tegument and negative impact of siRNA-based gene silencing on worm surface structure and egg hatching in Schistosoma japonicum.miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila.The human Lgl polarity gene, Hugl-2, induces MET and suppresses Snail tumorigenesis.Notch signals modulate lgl mediated tumorigenesis by the activation of JNK signaling.

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P2860

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

http://www.wikidata.org/entity/Q37480767

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on May 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

@en

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

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type

label

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

@en

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

@nl

prefLabel

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

@en

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

@nl

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138920208784340786

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Current Genomics

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Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling

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F Froldi

http://www.w3.org/2001/XMLSchema#string

F Garoia

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F Parisi

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G Tomba

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M Ziosi

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P2860

The Hallmarks of Cancer

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Putting tumours in context

hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

Developmental compartmentalisation of the wing disk of Drosophila

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

Molecular requirements for epithelial-mesenchymal transition during tumor progression

aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia.

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147-154

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scholarly article

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10.2174/138920208784340786

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3

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9

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Annalisa Pession

Daniela Grifoni

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2008-05-01T00:00:00Z

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24425654

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19440511

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2679652

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