A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase.
about
A rescue act: Translesion DNA synthesis past N(2) -deoxyguanosine adductsAn active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agentsA chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivoUmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs.Selection of dinB alleles suppressing survival loss upon dinB overexpression in Escherichia coli.Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coliGenetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass.Polynucleobacter necessarius, a model for genome reduction in both free-living and symbiotic bacteria.Translesion DNA synthesis and mutagenesis in prokaryotes.The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.Translesion DNA Synthesis.Efficient extension of slipped DNA intermediates by DinB is required to escape primer template realignment by DnaQ.Synthetic nucleotides as probes of DNA polymerase specificity.A single residue unique to DinB-like proteins limits formation of the polymerase IV multiprotein complex in Escherichia coli.Multiple strategies for translesion synthesis in bacteriaVariants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesion synthesis past a benzo[a]pyrene dG adduct.RNA Primer Extension Hinders DNA Synthesis by Escherichia coli Mutagenic DNA Polymerase IV.New discoveries linking transcription to DNA repair and damage tolerance pathways.Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV).Steric gate residues of Y-family DNA polymerases DinB and pol kappa are crucial for dNTP-induced conformational change.SOE-LRed: A simple and time-efficient method to localize genes with point mutations onto the Escherichia coli chromosome.Structural model of the Y-Family DNA polymerase V/RecA mutasome.The DinB•RecA complex of Escherichia coli mediates an efficient and high-fidelity response to ubiquitous alkylation lesions.
P2860
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P2860
A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase.
description
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name
A DinB variant reveals diverse ...... by a Y-family DNA polymerase.
@en
A DinB variant reveals diverse ...... by a Y-family DNA polymerase.
@nl
type
label
A DinB variant reveals diverse ...... by a Y-family DNA polymerase.
@en
A DinB variant reveals diverse ...... by a Y-family DNA polymerase.
@nl
prefLabel
A DinB variant reveals diverse ...... by a Y-family DNA polymerase.
@en
A DinB variant reveals diverse ...... by a Y-family DNA polymerase.
@nl
P2093
P2860
P356
P1476
A DinB variant reveals diverse ...... n by a Y-family DNA polymerase
@en
P2093
James C Delaney
John M Essigmann
Susan E Cohen
P2860
P304
21137-21142
P356
10.1073/PNAS.0907257106
P407
P577
2009-11-30T00:00:00Z