Genome-wide mapping of PiggyBac transposon integrations in primary human T cells. - Wikidata - wikimedia - TriplyDB

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

http://www.wikidata.org/entity/Q37485093

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Comparative analysis of transposable element vector systems in human cells The Sleeping Beauty transposon system: a non-viral vector for gene therapy Applications of DNA integrating elements: Facing the bias bully Retroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectives Simple and efficient methods for enrichment and isolation of endonuclease modified cells TrAmplification of Human Dental Follicle Cells by piggyBac Transposon - Mediated Reversible Immortalization System DNA transposon-based gene vehicles - scenes from an evolutionary drive Comparative analysis of the recently discovered hAT transposon TcBuster in human cells Genome-wide target profiling of piggyBac and Tol2 in HEK 293: pros and cons for gene discovery and gene therapy Ultrasound directs a transposase system for durable hepatic gene delivery in mice piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies.Helper-independent piggyBac plasmids for gene delivery approaches: strategies for avoiding potential genotoxic effects.Excision efficiency is not strongly coupled to transgenic rate: cell type-dependent transposition efficiency of sleeping beauty and piggyBac DNA transposons CHO cell lines generated by PiggyBac transposition.Rapid recombinant protein production from pools of transposon-generated CHO cells.The human application of gene therapy to re-program T-cell specificity using chimeric antigen receptors The impact of cHS4 insulators on DNA transposon vector mobilization and silencing in retinal pigment epithelium cells.A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells.Chromatin landscapes of retroviral and transposon integration profiles Hybrid nonviral/viral vector systems for improved piggyBac DNA transposon in vivo delivery PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.Hyperactive piggyBac gene transfer in human cells and in vivo.piggyBac-ing models and new therapeutic strategies.A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon A resurrected mammalian hAT transposable element and a closely related insect element are highly active in human cell culture.Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits.Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.Analysis of PBase Binding Profile Indicates an Insertion Target Selection Mechanism Dependent on TTAA, But Not Transcriptional Activity Effective Targeted Gene Knockdown in Mammalian Cells Using the piggyBac Transposase-based Delivery System.Genetic redirection of T cells for cancer therapy.The expanding universe of transposon technologies for gene and cell engineering.Size matters: versatile use of PiggyBac transposons as a genetic manipulation tool.Recent developments in transposon-mediated gene therapy.ErbB-targeted CAR T-cell immunotherapy of cancer.Manipulating piggyBac transposon chromosomal integration site selection in human cells Secretome profiles of immortalized dental follicle cells using iTRAQ-based proteomic analysis.Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials.The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability.Mesothelin-targeting chimeric antigen receptor-modified T cells by piggyBac transposon system suppress the growth of bile duct carcinoma.The Production of Pluripotent Stem Cells from Mouse Amniotic Fluid Cells Using a Transposon System.

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Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

http://www.wikidata.org/entity/Q37485093

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on October 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

@en

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

@nl

type

label

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

@en

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

@nl

prefLabel

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

@en

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

@nl

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Journal of Immunotherapy

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Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.

@en

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Aparna Kaja

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Claudia Kettlun

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Cliona M Rooney

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Daniel L Galvan

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Laurence J N Cooper

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Matthew H Wilson

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Yozo Nakazawa

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P2860

Cancer regression in patients after transfer of genetically engineered lymphocytes

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

Shielding of sleeping beauty DNA transposon-delivered transgene cassettes by heterologous insulators in early embryonal cells

Postintegrative gene silencing within the Sleeping Beauty transposition system

Selection of target sites for mobile DNA integration in the human genome

High-resolution genome-wide mapping of transposon integration in mammals.

Transcription start regions in the human genome are favored targets for MLV integration

HIV-1 integration in the human genome favors active genes and local hotspots

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

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837-844

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10.1097/CJI.0B013E3181B2914C

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8

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2796288

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