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Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with MesotrypsinChymotrypsin C mutations in chronic pancreatitis.Chronic Pancreatitis: A ReviewTransgenic expression of pancreatic secretory trypsin inhibitor-1 rescues SPINK3-deficient mice and restores a normal pancreatic phenotypeA conservative assessment of the major genetic causes of idiopathic chronic pancreatitis: data from a comprehensive analysis of PRSS1, SPINK1, CTRC and CFTR genes in 253 young French patientsCommon genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.Complete ascertainment of intragenic copy number mutations (CNMs) in the CFTR gene and its implications for CNM formation at other autosomal lociAutophagy in alcohol-induced multiorgan injury: mechanisms and potential therapeutic targetsCharacterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription.Endoplasmic reticulum stress is chronically activated in chronic pancreatitisGenome-wide association study identifies multiple susceptibility loci for pancreatic cancer.Pathophysiology of chronic pancreatitis.Risk factors for pancreatic cancer: underlying mechanisms and potential targets.Genetics and treatment options for recurrent acute and chronic pancreatitis.Antioxidative phytoceuticals to ameliorate pancreatitis in animal models: an answer from nature.Assessing the pathological relevance of SPINK1 promoter variants.Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1β in the pancreas.Functional characteristics of L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese.Surgical Management of Chronic Pancreatitis.Framework for interpretation of genetic variations in pancreatitis patients.Assessing the Disease-Liability of Mutations in CFTRPathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitisLoss of acinar cell IKKα triggers spontaneous pancreatitis in mice.What is personalized medicine and what should it replace?Genetic risk factors for pancreatic disorders.Genetics of alcoholic and nonalcoholic pancreatitis.Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis.Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice.New insights into the pathogenesis of pancreatitis.Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiencySpecialized roles for cysteine cathepsins in health and disease.Molecular mechanisms of pancreatic injury.Genetics of pancreatitis: an update for clinicians and genetic counselors.Pathogenic mechanisms of acute pancreatitis.Genetics of pancreatitis with a focus on the pancreatic ducts.Genophenotypic Analysis of Pediatric Patients With Acute Recurrent and Chronic PancreatitisDisrupted post-transcriptional regulation of the cystic fibrosis transmembrane conductance regulator (CFTR) by a 5'UTR mutation is associated with a CFTR-related disease.Calcium sensing receptor mutations implicated in pancreatitis and idiopathic epilepsy syndrome disrupt an arginine-rich retention motif.Functional significance of SPINK1 promoter variants in chronic pancreatitis.Association of claudin2 and PRSS1-PRSS2 polymorphisms with idiopathic recurrent acute and chronic pancreatitis: A case-control study from India.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Chronic pancreatitis: genetics and pathogenesis.
@en
Chronic pancreatitis: genetics and pathogenesis.
@nl
type
label
Chronic pancreatitis: genetics and pathogenesis.
@en
Chronic pancreatitis: genetics and pathogenesis.
@nl
prefLabel
Chronic pancreatitis: genetics and pathogenesis.
@en
Chronic pancreatitis: genetics and pathogenesis.
@nl
P1476
Chronic pancreatitis: genetics and pathogenesis.
@en
P2093
Claude Férec
Jian-Min Chen
P356
10.1146/ANNUREV-GENOM-082908-150009
P577
2009-01-01T00:00:00Z