Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding.
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Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasmInflammation induced loss of skeletal muscleDifferential interactions of Id proteins with basic-helix-loop-helix transcription factorsTGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3MyoD is indispensable for muscle-specific alternative splicing in mouse mitochondrial ATP synthase gamma-subunit pre-mRNASyndecan-1 expression is down-regulated during myoblast terminal differentiation. Modulation by growth factors and retinoic acidA myogenic factor from sea urchin embryos capable of programming muscle differentiation in mammalian cells.Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts.cdk1- and cdk2-mediated phosphorylation of MyoD Ser200 in growing C2 myoblasts: role in modulating MyoD half-life and myogenic activity.Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications.Identification of differentially regulated secretome components during skeletal myogenesisExpression and differential regulation of Id1, a dominant negative regulator of basic helix-loop-helix transcription factors, in glomerular mesangial cells.Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis.TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members.Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage.Ras p21Val inhibits myogenesis without altering the DNA binding or transcriptional activities of the myogenic basic helix-loop-helix factors.Tumor cell complementation groups based on myogenic potential: evidence for inactivation of loci required for basic helix-loop-helix protein activitySignaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesisSequences of acetyl CoA carboxylase promoter for tumour necrosis factor actionTransforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation.fos/jun repression of cardiac-specific transcription in quiescent and growth-stimulated myocytes is targeted at a tissue-specific cis element.Induction of heparin-binding EGF-like growth factor expression during myogenesis. Activation of the gene by MyoD and localization of the transmembrane form of the protein on the myotube surface.Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2.Cyclic AMP-dependent protein kinase inhibits the activity of myogenic helix-loop-helix proteins.Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products.Regulation of the human cardiac/slow-twitch troponin C gene by multiple, cooperative, cell-type-specific, and MyoD-responsive elementsTransforming growth factor beta induces myoblast differentiation in the presence of mitogensHepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice.miRNAS in normal and diseased skeletal muscle.Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters.Secretome Analysis of Skeletal Myogenesis Using SILAC and Shotgun Proteomics.The role of TGF-β1 during skeletal muscle regeneration.The Rho family G proteins play a critical role in muscle differentiationRole of endogenous TGF-β family in myogenic differentiation of C2C12 cells.Terminal differentiation of Sol 8 myoblasts is retarded by a transforming growth factor-beta autocrine regulatory loopTGF-beta-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation.Systematic analysis of the TGF-beta/Smad signalling pathway in the rhabdomyosarcoma cell line RD.Fibroblast growth factor inhibits MRF4 activity independently of the phosphorylation status of a conserved threonine residue within the DNA-binding domain.Negative regulation of transcription in eukaryotes.
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Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Transforming growth factor bet ...... sm independent of DNA binding.
@en
Transforming growth factor bet ...... sm independent of DNA binding.
@nl
type
label
Transforming growth factor bet ...... sm independent of DNA binding.
@en
Transforming growth factor bet ...... sm independent of DNA binding.
@nl
prefLabel
Transforming growth factor bet ...... sm independent of DNA binding.
@en
Transforming growth factor bet ...... sm independent of DNA binding.
@nl
P2093
P2860
P356
P1476
Transforming growth factor bet ...... sm independent of DNA binding.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.9.3822
P407
P577
1991-05-01T00:00:00Z