HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias. - Wikidata - wikimedia - TriplyDB

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

http://www.wikidata.org/entity/Q37503220

about

Transcriptional network control of normal and leukaemic haematopoiesis Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets The LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity.High expression of LMO2 predicts a favorable outcome in adult patients with BCR/ABL negative B-cell acute lymphoblastic leukemia.LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways.Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation.

P2860

Q27005940-EDD14270-3F2F-4607-ABE3-EC5DE6EF75EE Q28082027-8906187B-74C9-455A-99B8-436270C7A400 Q35687910-231C6B2C-BC17-44B0-AD0D-70F99A409DBF Q36640231-6B67BE75-1E91-48C7-9268-CD05A4E597FE Q37499781-85D1EFC5-3B47-47CD-9BE4-C7726739B4E8 Q48267075-957C03E2-E1EA-4BE9-8C3F-432D940201E7

P2860

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

http://www.wikidata.org/entity/Q37503220

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 27 May 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

@en

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

@nl

type

label

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

@en

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

@nl

prefLabel

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

@en

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

@nl

P1433

Q37503220-0E4E2F49-3811-4340-AD59-CB0AAC95B428

P1476

Q37503220-04FA6E30-BACA-4786-9014-A4BC3D6B9250

P2093

Q37503220-6012CEC4-61C1-4DE1-BE39-FB43B946038D

Q37503220-6BE56EB5-72ED-49C5-A757-B598AD6E3326

Q37503220-8964E039-EA92-4B01-9C86-C27225BACB39

Q37503220-936FE24C-3A50-443B-80A8-06E305D4F7D6

Q37503220-99C79BB5-E8F4-40D3-AC97-C271D1695710

Q37503220-DC92A828-D734-42DE-A286-6BAE42AE3576

Q37503220-FEE25C5B-C7CE-4EBC-BC3C-489FFD850553

P2860

Q37503220-01C2F328-E5AB-4E8A-AD58-16827532352E

Q37503220-0DF427DA-426F-41CF-AAAB-717C3181938C

Q37503220-0ECADC66-E752-4740-B32D-8BDEF0AB5224

Q37503220-1A5B74DE-8900-4FE0-A4F9-FBBD20E6FE34

Q37503220-1D5364D8-641B-400B-9E43-4A2E768BEEA8

Q37503220-200388B1-E1C0-4541-8973-86E32B6BFFCF

Q37503220-29BA5CD4-CBEE-4EA0-8D47-2B10E454A0B7

Q37503220-359C06D7-8015-4122-8F01-056B3734BE78

Q37503220-408A424B-2D27-4447-8F04-12489D90D6EF

Q37503220-40EAE36B-D3F3-4DA4-B53F-49A2A59FB0DF

P2888

Q37503220-6C3F2243-25F6-45FD-A9F3-750811527DB4

P304

Q37503220-24071B92-07CC-49C1-9FFF-18AA999D2644

P31

Q37503220-3E29954D-D457-440E-8635-F1EB87B62AAD

P356

Q37503220-83C29DD3-3C1B-46AE-964D-D7E321C74D41

P407

Q37503220-8435EFF1-EC86-4AE2-827C-BB27D85F94F4

P433

Q37503220-58959886-0A75-4690-BA7B-4B5CD810162C

P478

Q37503220-3078C2FF-FF1F-4CDC-A25B-38F74B696AEB

P50

Q37503220-19FB92FA-6AA0-4468-943A-012A88A1DEF5

Q37503220-1A0D986F-6D0A-4C79-8E06-5FC616FF700D

Q37503220-2D7C7D02-39F0-4AD9-A2EB-95A737B4B403

Q37503220-B144D256-81DB-46F6-9F29-79F5276A19B6

P577

Q37503220-5CC3B040-6E78-4EEE-8D88-92D82D43D8E7

P5875

Q37503220-BDD9F1E3-C3A6-43CD-AFAC-36AB9693FCE3

P698

Q37503220-740EB94F-8ECA-42A2-A4F7-D3C6242AD900

P921

Q37503220-81E261AB-A842-44C2-8E65-FF867D266972

P932

Q37503220-7EFC0C93-7E0F-4780-9B53-8E7C532D6FE0

P356

P1433

P1476

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias

@en

P2093

A Joshi

http://www.w3.org/2001/XMLSchema#string

C Pridans

http://www.w3.org/2001/XMLSchema#string

E Gudgin

http://www.w3.org/2001/XMLSchema#string

J Kikuchi

http://www.w3.org/2001/XMLSchema#string

J-R Landry

http://www.w3.org/2001/XMLSchema#string

S Kinston

http://www.w3.org/2001/XMLSchema#string

W-I Chan

http://www.w3.org/2001/XMLSchema#string

P2860

Human homeobox HOXA7 regulates keratinocyte transglutaminase type 1 and inhibits differentiation

TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11)

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Two distinct sources for a population of maturing axial progenitors

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

P2888

P304

5471-5480

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/ONC.2013.175

http://www.w3.org/2001/XMLSchema#string

P407

P433

48

http://www.w3.org/2001/XMLSchema#string

P478

32

http://www.w3.org/2001/XMLSchema#string

P50

Berthold Gottgens

Fernando J Calero-Nieto

Nicolas Bonadies

P577

2013-05-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

236939797

http://www.w3.org/2001/XMLSchema#string

P698

23708655

http://www.w3.org/2001/XMLSchema#string

P921

P932

3898495

http://www.w3.org/2001/XMLSchema#string