3-Hydroxy-3-methylglutaryl-CoA reductase: a transmembrane glycoprotein of the endoplasmic reticulum with N-linked "high-mannose" oligosaccharides.
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Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liverDiversity of degradation signals in the ubiquitin-proteasome systemImmunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulumIdentifying mutations in duplicated functions in Saccharomyces cerevisiae: recessive mutations in HMG-CoA reductase genesLong-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry.Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.An ultrastructural stereological study of accessory adrenocortical glands in bilaterally adrenalectomised rats.Long term effects of the hypocholesterolaemic drug 4-aminopyrazolo-pyrimidine on the zona fasciculata of the rat adrenal cortex.Effects of ACTH and aminoglutethimide administration on the morphological and functional responses of rat adrenal zona fasciculata to a prolonged treatment with 4-aminopyrazolo-pyrimidineExpression of the Saccharomyces cerevisiae glycoprotein invertase in mouse fibroblasts: glycosylation, secretion, and enzymatic activity.Cloning, sequencing, and overexpression of mvaA, which encodes Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl coenzyme A reductase.Biosynthesis and processing of ribophorins in the endoplasmic reticulum.Processing of the asparagine-linked oligosaccharides of secreted and intracellular forms of the vesicular stomatitis virus G protein: in vivo evidence of Golgi apparatus compartmentalizationProcessing of the rough endoplasmic reticulum membrane glycoproteins of rotavirus SA11.Retention of membrane proteins by the endoplasmic reticulumImmunolocalization of the oligosaccharide trimming enzyme glucosidase II3-Hydroxy-3-methylglutaryl coenzyme A reductase localization in rat liver peroxisomes and microsomes of control and cholestyramine-treated animals: quantitative biochemical and immunoelectron microscopical analyses.Partial deletion of membrane-bound domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase eliminates sterol-enhanced degradation and prevents formation of crystalloid endoplasmic reticulumReconstitution of transport of vesicular stomatitis virus G protein from the endoplasmic reticulum to the Golgi complex using a cell-free system.Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulumThe G protein of vesicular stomatitis virus has free access into and egress from the smooth endoplasmic reticulum of UT-1 cells.Biogenesis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an integral glycoprotein of the endoplasmic reticulumDifferential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expressionGenetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductaseDevelopmental and metabolic regulation of the Drosophila melanogaster 3-hydroxy-3-methylglutaryl coenzyme A reductase.Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesisSterols accelerate degradation of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase encoded by a constitutively expressed cDNA.3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells.Calmodulin-binding proteins as calpain substrates.Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein.Purification, characterization, and cloning of a eubacterial 3-hydroxy-3-methylglutaryl coenzyme A reductase, a key enzyme involved in biosynthesis of terpenoids.Applications of recombinant DNA technology to studies of metabolic regulationDislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation.Ubiquitin is conjugated by membrane ubiquitin ligase to three sites, including the N terminus, in transmembrane region of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for sterol-regulated enzyme degradation.N-glycan structure of a short-lived variant of ribophorin I expressed in the MadIA214 glycosylation-defective cell line reveals the role of a mannosidase that is not ER mannosidase I in the process of glycoprotein degradation.The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase.3-Hydroxy-3-methylglutaryl coenzyme A reductase in anencephalic and normal human fetal liver.Impaired regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation in lovastatin-resistant cells.The role of N-linked glycosylation in the regulation of activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and proliferation of SV40-transformed 3T3 cells.
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P2860
3-Hydroxy-3-methylglutaryl-CoA reductase: a transmembrane glycoprotein of the endoplasmic reticulum with N-linked "high-mannose" oligosaccharides.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
3-Hydroxy-3-methylglutaryl-CoA ...... igh-mannose" oligosaccharides.
@en
3-Hydroxy-3-methylglutaryl-CoA ...... igh-mannose" oligosaccharides.
@nl
type
label
3-Hydroxy-3-methylglutaryl-CoA ...... igh-mannose" oligosaccharides.
@en
3-Hydroxy-3-methylglutaryl-CoA ...... igh-mannose" oligosaccharides.
@nl
prefLabel
3-Hydroxy-3-methylglutaryl-CoA ...... igh-mannose" oligosaccharides.
@en
3-Hydroxy-3-methylglutaryl-CoA ...... igh-mannose" oligosaccharides.
@nl
P2093
P2860
P921
P356
P1476
3-Hydroxy-3-methylglutaryl-CoA ...... igh-mannose" oligosaccharides.
@en
P2093
G N DeMartino
J L Goldstein
R D Cummings
R G Anderson
P2860
P304
P356
10.1073/PNAS.80.23.7165
P407
P577
1983-12-01T00:00:00Z