Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells.
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Developmental Dynamics of Rett SyndromeDNA modifications: function and applications in normal and disease StatesDevelopment of a Novel AAV Gene Therapy Cassette with Improved Safety Features and Efficacy in a Mouse Model of Rett SyndromeImproved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery.Experimental Autoimmune Encephalomyelitis (EAE)-Induced Elevated Expression of the E1 Isoform of Methyl CpG Binding Protein 2 (MeCP2E1): Implications in Multiple Sclerosis (MS)-Induced Neurological Disability and Associated Myelin DamageCellular commitment in the developing cerebellumBrain region-specific expression of MeCP2 isoforms correlates with DNA methylation within Mecp2 regulatory elements.MECP2, a gene associated with Rett syndrome in humans, shows conserved coding regions, independent Alu insertions, and a novel transcript across primate evolutionEpigenetic DNA Demethylation Causes Inner Ear Stem Cell Differentiation into Hair Cell-Like CellsMeCP2-Related Diseases and Animal Models.Rett syndrome and MeCP2.MeCP2: multifaceted roles in gene regulation and neural development.Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS).Bioinformatic Analysis of DNA Methylation in Neural Progenitor Cell Models of Alcohol Abuse.Neural stem cell replacement: a possible therapy for neurodevelopmental disorders?Ethanol deregulates Mecp2/MeCP2 in differentiating neural stem cells via interplay between 5-methylcytosine and 5-hydroxymethylcytosine at the Mecp2 regulatory elements.Editorial (Thematic Issue: NeuroEpigenetics and Neurodevelopmental Disorders: From Molecular Mechanisms to Cell Fate Commitments of the Brain Cells and Human Disease).MeCP2 Modulates Sex Differences in the Postsynaptic Development of the Valproate Animal Model of Autism.Transcriptional Regulation by MECP2Regulation of MECP2 expression and activity
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Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells.
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2013 nî lūn-bûn
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name
Decitabine alters the expressi ...... elements in neural stem cells.
@en
Decitabine alters the expressi ...... elements in neural stem cells.
@nl
type
label
Decitabine alters the expressi ...... elements in neural stem cells.
@en
Decitabine alters the expressi ...... elements in neural stem cells.
@nl
prefLabel
Decitabine alters the expressi ...... elements in neural stem cells.
@en
Decitabine alters the expressi ...... elements in neural stem cells.
@nl
P2860
P356
P1433
P1476
Decitabine alters the expressi ...... elements in neural stem cells.
@en
P2093
Robby M Zachariah
Vichithra R B Liyanage
P2860
P2888
P356
10.1186/2040-2392-4-46
P577
2013-11-15T00:00:00Z
P5875
P6179
1020061695