A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
about
Reactive Oxygen Species-Mediated Mechanisms of Action of Targeted Cancer TherapyThe KISS1 metastasis suppressor appears to reverse the Warburg effect by shifting from glycolysis to mitochondrial beta-oxidation.Mitochondrial dynamics as regulators of cancer biology.NO control of mitochondrial function in normal and transformed cells.PGC-1 Coactivators: Shepherding the Mitochondrial Biogenesis of Tumors.Cellular glycosylation senses metabolic changes and modulates cell plasticity during epithelial to mesenchymal transition.Cancer: Linking Powerhouses to Suicidal Bags.Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer.Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.Cancer, Oxidative Stress, and Metastasis.Super-enhancers define a proliferative PGC-1α-expressing melanoma subgroup sensitive to BET inhibition.PGC1α: Friend or Foe in Cancer?A PGC1β genetic variant associated with nevus count and melanoma mortality.Metabolism and Transcription in Cancer: Merging Two Classic Tales.Roles of Mitochondrial DNA Signaling in Immune Responses.Mitochondrial Metabolism: Yin and Yang for Tumor Progression.ERRα Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-Elevated Melanomas.Targeting the duality of cancer.PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect.Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor.Deciphering the Dichotomous Effects of PGC-1α on Tumorigenesis and Metastasis.Amino Acid Signature in Human Melanoma Cell Lines from Different Disease Stages.Homeostasis, regeneration and tumour formation in the mammalian epidermis
P2860
Q33862425-15AD2A75-5741-4457-8491-1B811905ED37Q38735057-6F727133-2AE5-444D-9E13-4571F4460CCFQ39084933-77D9FAD4-6FFF-469D-92DA-32DCA973A29CQ39143236-588166B6-FF95-46DA-A021-5D57825BB1F8Q39368524-6408D252-ED0D-42AA-86D1-EDAF721AF9EEQ39443781-11FBB270-50B1-4A6E-A293-3E61949C5ED2Q41440316-05B4BF44-4C59-4E0B-854F-A1BA7D2DCD3FQ42375241-A9B5B3F2-90A4-454D-A9D9-FEE61AB7DD30Q45073569-3B551A0B-1E0A-43E7-AD1B-F066A7D8F1ACQ46433308-AC6D7253-D86D-4315-9856-334D5BACEBC9Q47750108-36AACB81-B532-4A9C-916C-78C713FE077FQ47844268-72217B2C-60E0-4545-A514-65D45FB046D7Q48099889-65EAAF6E-2B7C-40DB-B298-CAE71A509007Q49306241-094D8555-9CA7-4DBC-AC88-0F4C7EDFFBC7Q49605167-0E85F116-C0FB-48F8-926F-C9D5725CB94CQ49918002-5E981B21-4B5D-403D-819F-95DD97377439Q50952961-5DFC54D2-557C-40B0-87B3-04FDE473377AQ52539731-4F60B415-F205-4C16-BE44-08294756E6ACQ52560186-35AA6EBA-34AA-42E2-86E6-DE74CEEFE58BQ53076500-E01F7B9C-B3F1-49EC-A981-9D73DB54B84DQ55008290-0A8FD1D1-A7B4-4FE5-807A-94F41B806A67Q55091781-295AE745-28DB-4EB3-8F3E-34F64EEE08A0Q57385046-01EF79AB-2FFA-47D9-A5A7-6D1D232F288B
P2860
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 31 August 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
@en
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
@nl
type
label
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
@en
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
@nl
prefLabel
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
@en
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
@nl
P2093
P2860
P356
P1433
P1476
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
@en
P2093
Ajith Thomas
Ji-Hong Lim
Pere Puigserver
Scott R Granter
Yoonjin Lee
P2860
P2888
P304
P356
10.1038/NATURE19347
P407
P577
2016-08-31T00:00:00Z
P6179
1018481217