Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors.
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Optimized expression and specific activity of IL-12 by directed molecular evolution.Enhancing the immunogenicity of exogenous hepatitis B surface antigen-based vaccines for MHC-I-restricted T cells.Gene therapy and dermatology: more than just skin deep.Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL.Measles virus DNA vaccination: antibody isotype is determined by the method of immunization and by the nature of both the antigen and the coimmunized antigen.Genetic vaccination against experimental infection with myotropic parasite strains of Trypanosoma cruzi.The production and applications of genetically modified skin cells.Gene therapy in wound repair and regeneration.Particle-mediated gene therapy of wounds.Targeting the tumor microenvironment to enhance antitumor immune responsesCombined suicide and cytokine gene therapy for peritoneal carcinomatosisTopical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin.Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma.Characterization of an IL-12 p40/p35 Truncated Fusion Protein That can Inhibit the Action of IL-12.A multi-trimeric fusion of CD40L and gp100 tumor antigen activates dendritic cells and enhances survival in a B16-F10 melanoma DNA vaccine modelContinuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therapy.Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect.HBV DNA vaccine with adjuvant cytokines induced specific immune responses against HBV infectionInterleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression.Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1beta converting enzyme cDNA.Electroporation driven delivery of both an IL-12 expressing plasmid and cisplatin synergizes to inhibit B16 melanoma tumor growth through an NK cell mediated tumor killing mechanism.Cutaneous gene therapy.Gene Therapy against Murine Melanoma B16F10-Nex2 Using IL-13Ralpha2-Fc Chimera and Interleukin 12 in Association with a Cyclopalladated DrugDNA vaccination and gene therapy: optimization and delivery for cancer therapy.Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts.In vivo tumor transfection with superantigen plus cytokine genes induces tumor regression and prolongs survival in dogs with malignant melanoma.Identification of iGb3 and iGb4 in melanoma B16F10-Nex2 cells and the iNKT cell-mediated antitumor effect of dendritic cells primed with iGb3Micro- and nanotechnologies for intracellular delivery.Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.Gene therapy with interleukin-10 receptor and interleukin-12 induces a protective interferon-γ-dependent response against B16F10-Nex2 melanoma.Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production.Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy.Molecular strategies for improving cytokine transgene expression in normal and malignant tissues.Thyroid cancer immuno-therapy with retroviral and adenoviral vectors expressing granulocyte macrophage colony stimulating factor and interleukin-12 in a rat model.Relative promoter strengths in four human prostate cancer cell lines evaluated by particle bombardment-mediated gene transfer.Fas-Fas ligand signaling pathway mediates an interleukin-12-induced rejection of a murine prostate tumor system.Immunotherapy with recombinant SFV-replicons expressing the P815A tumor antigen or IL-12 induces tumor regression.Adenovirus-mediated interleukin-12 gene therapy for prostate cancer: suppression of orthotopic tumor growth and pre-established lung metastases in an orthotopic model.Local administration of IL-12-transfected dendritic cells induces antitumor immune responses to colon adenocarcinoma in the liver in mice.Long-lasting gene expression by particle-mediated intramuscular transfection modified with bupivacaine: combinatorial gene therapy with IL-12 and IL-18 cDNA against rat sarcoma at a distant site.
P2860
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P2860
Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Gene gun-mediated skin transfe ...... and metastatic murine tumors.
@en
Gene gun-mediated skin transfe ...... and metastatic murine tumors.
@nl
type
label
Gene gun-mediated skin transfe ...... and metastatic murine tumors.
@en
Gene gun-mediated skin transfe ...... and metastatic murine tumors.
@nl
prefLabel
Gene gun-mediated skin transfe ...... and metastatic murine tumors.
@en
Gene gun-mediated skin transfe ...... and metastatic murine tumors.
@nl
P2093
P2860
P356
P1476
Gene gun-mediated skin transfe ...... and metastatic murine tumors.
@en
P2093
Rakhmilevich AL
P2860
P304
P356
10.1073/PNAS.93.13.6291
P407
P577
1996-06-01T00:00:00Z