Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis. - Wikidata - wikimedia - TriplyDB

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

http://www.wikidata.org/entity/Q37524234

about

Myh11(R247C/R247C) mutations increase thoracic aorta vulnerability to intramural damage despite a general biomechanical adaptivity.Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves.Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties.The Pathogenic Transforming Growth Factor-β Overdrive Hypothesis in Aortic Aneurysms and Dissections: A Mirage?Computational modelling suggests good, bad and ugly roles of glycosaminoglycans in arterial wall mechanics and mechanobiology Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function Hypertension overrides the protective effect of female hormones on the development of aortic aneurysm secondary to Alk5 deficiency via ERK activation.Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections.TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.Preexisting smooth muscle cells contribute to neointimal cell repopulation at an incidence varying widely among individual lesions.Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-β/Smad pathway in vascular smooth muscle cells Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice Insights into ascending aortic aneurysm pathogenesis using in vivo and ex vivo imaging systems in angiotensin II-infused mice Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFβ)-dependent smooth muscle cell phenotype modulation.Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events.Experimental in vivo and ex vivo models for the study of human aortic dissection: promises and challenges Smooth muscle cell-specific Tgfbr1 deficiency attenuates neointimal hyperplasia but promotes an undesired vascular phenotype for injured arteries.Specific circulating microRNA signature of bicuspid aortic valve disease.A healthy tension in translational research.Genetics of hereditary large vessel diseases.Comparison of 10 murine models reveals a distinct biomechanical phenotype in thoracic aortic aneurysms.Inhibition of the mTOR pathway in abdominal aortic aneurysm: implications of smooth muscle cell contractile phenotype, inflammation, and aneurysm expansion.Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling TGF-β Family Signaling in Connective Tissue and Skeletal Diseases.DPY-17 and MUA-3 Interact for Connective Tissue-Like Tissue Integrity in Caenorhabditis elegans: A Model for Marfan Syndrome Vascular Smooth Muscle Cells.Cell biology. Dysfunctional mechanosensing in aneurysms.Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression The future is now: frontiers on display at Yale-NAVBO cardiovascular inflammation and remodeling symposium 2014.AT1 receptor antagonism to reduce aortic expansion in Marfan syndrome: lost in translation or in need of different interpretation?Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma.NADPH oxidase 4 attenuates cerebral artery changes during the progression of Marfan syndrome.An X-linked Myh11-CreERT2 mouse line resulting from Y to X chromosome-translocation of the Cre allele.Transforming Growth Factor-β1 Inhibits Pseudoaneurysm Formation After Aortic Patch Angioplasty.Biomechanical Phenotyping of the Murine Aorta: What Is the Best Control?Further Evidence Supporting a Protective Role of Transforming Growth Factor-β (TGFβ) in Aortic Aneurysm and Dissection.

P2860

Q27310169-CD8AF77B-395F-4DC3-BA42-FB9758A0C7C1 Q27311289-79F3A5A2-50FC-4C26-B59A-E74E561BDE87 Q27311656-8860F472-D66B-4155-9DC0-19B8CA886F8D Q30749956-B9FF3270-757D-48CD-B963-480964216B2F Q33736775-851446A0-ABA3-46E9-AA5B-0A62D98C43C2 Q34398882-88C7D104-FC00-42C6-9F12-68B69304637B Q34453805-E53532BB-0138-46F5-8CBA-CE42F8E625B3 Q35115818-3FF97110-FE1D-4365-A2BC-9789F9449270 Q35224497-C6A42412-4D7E-4AC4-B6A5-1275350D84EA Q35571996-C5DCAB43-624A-43E0-84FE-2E5BFCF65340 Q35996913-C3221149-861A-4655-A347-6E5DA66FAC7E Q36300421-09A7B633-8781-4369-B910-2112D9F2BCB5 Q36447558-1AE53CAE-25B3-46A4-942A-176F5C3B641F Q36499485-AFADD22E-648B-4018-9FC7-52BBB1746789 Q36551449-507EE789-B4C7-45EA-BFB8-E12E7F6105D0 Q37208735-61EAFB84-FBC3-4E7D-B155-DAF429D53E14 Q37260797-8F79DC31-0BBF-4072-8267-F8A0B94511EF Q37339708-5E0C09C6-BF8C-4492-AF72-B0533F4745D7 Q37553691-341297D8-8166-455D-8D6E-A70969434437 Q37710674-77DB0CDA-3559-4588-9E81-986690C082BA Q37747621-E7C7D3C6-7613-47D4-B27A-417591918E4D Q38592372-BA474F2D-0358-40AF-9AAD-F2D18C3C9A78 Q38601760-7F8A0FD5-C9A6-4B3D-9850-4D3A9FED8A45 Q38793690-A18C920A-FBDE-4468-A637-93973B63B081 Q38954597-A90A5504-FAD4-4D91-A49B-C53FEF876306 Q39001215-242F1799-BEF7-41F6-BBF5-1FC115CA583B Q39155183-C967505C-9C0C-4933-A7E6-8D8E151BB122 Q41586331-6CBEBBDA-6380-42C6-A386-7D15091E8FCD Q41633099-A190741D-CF86-4F4A-8E41-794B5166201F Q41985150-A5452D8E-6BF1-4760-AA7E-97A8CA45A2EA Q42336072-A2EE6B5E-F01A-4F26-8A2F-B671B5998FF8 Q42434436-104D14A6-9133-48D8-88A6-AB93DB5FCB46 Q43056339-4DB13F11-174A-49A6-A0F0-968C5885C46C Q43117594-0C92A622-6092-4BCA-9CA6-CD6BF0E93A14 Q46301833-BE8D1308-AA7E-4ABE-BCDC-97DE3A3C07F3 Q46584807-CCC1E3E5-EF0E-4B25-BA3F-7249D9685899 Q47136592-2E79A592-F015-48C2-BBAC-CC3098C1D1B4 Q47340304-50B54271-F5B3-457A-BA83-DCD9B9C9DACD Q47375871-6D1B3E5E-EE3C-4DDD-99A1-415EA171E427 Q47728737-A3D7EB68-B96B-405A-8033-3D56FCEF8926

P2860

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

http://www.wikidata.org/entity/Q37524234

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 09 January 2014

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

@en

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

@nl

type

label

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

@en

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

@nl

prefLabel

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

@en

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

@nl

P1433

Q37524234-536D64EA-A1EA-4A73-AFAF-34E107429DB6

P1476

Q37524234-97EB004E-19F5-456B-99A2-E7FAFD95785E

P2093

Q37524234-0D85CD17-5147-4011-AE2E-8E9270700053

Q37524234-3A9E3679-98F7-4E4E-95A9-544D5BAC9985

Q37524234-4073AC44-346A-4765-8FD7-0B9B8862BCF8

Q37524234-448286BF-A2EE-4D9D-BC2B-9F189C359645

Q37524234-5B46EDAE-07AB-4C12-9DE5-63C76AE598E1

Q37524234-86197F47-50BE-4B25-A8DD-6164584A172E

Q37524234-C5F46A00-54FD-4D5B-A900-B6BAF5358830

Q37524234-E7FB1FFB-5432-4781-925C-002152E08DEA

Q37524234-F4A9F9D3-206D-4C43-B0D7-71A44DA360C6

Q37524234-FD631D99-E3D3-4CD2-B177-8AEE4BD93C0F

P2860

Q37524234-00B477D1-6790-4D05-8AAF-C45AE7A57D1C

Q37524234-06A5F187-4FC1-45C3-9EDF-55AFCCBFA89C

Q37524234-0AA206EB-B3B3-4F9B-8D09-D6E7E0BDD76F

Q37524234-109A49AE-EBDC-4C54-AFD6-4D92D4412B83

Q37524234-12E1ADDB-E958-405A-BE75-485408F4CB22

Q37524234-13AECEEC-C2E5-48A2-9707-5199F2D5C3D9

Q37524234-13D7B2AB-DCA3-4D63-BB96-B809B51204F8

Q37524234-1581DAC5-71EB-4E06-A855-D95B294A8439

Q37524234-1DC73A82-1225-4ED1-8A81-E2A9DDD9865D

Q37524234-23967365-6864-4366-B2B6-A4B92F5B1E53

P304

Q37524234-822FA99E-4372-4327-9FE0-15C3DD742298

P31

Q37524234-E9EBC0CA-6C1A-4645-9ED3-149E5BADA06F

P356

Q37524234-EE3E06B9-A4F1-4918-849C-A8DDC04FA153

P407

Q37524234-17FA3093-6C6F-4EC8-83DD-B868E3714C9B

P433

Q37524234-6C4A468E-8988-4FFE-AFF8-967E27DB87E3

P478

Q37524234-A46C757B-4E20-4887-B633-BAB282E186D1

P50

Q37524234-5C9376C5-370A-4BB0-9162-FA8AE5CA8EC3

P577

Q37524234-2662A4DC-4AC5-45CC-A9F6-2DA7CDEBCBFF

P698

Q37524234-4D7F8682-350C-4D1E-8856-773D70B03B07

P921

Q37524234-73E13566-9C93-4DC7-A86A-2A7DAF70D493

P932

Q37524234-9612F8B2-C2F2-45CC-9035-6B77B816B799

P356

P1433

Journal of Clinical Investigation

P1476

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

@en

P2093

Arnar Geirsson

http://www.w3.org/2001/XMLSchema#string

George Tellides

http://www.w3.org/2001/XMLSchema#string

Harry C Dietz

http://www.w3.org/2001/XMLSchema#string

Jacopo Ferruzzi

http://www.w3.org/2001/XMLSchema#string

Jay D Humphrey

http://www.w3.org/2001/XMLSchema#string

Jing Zhou

http://www.w3.org/2001/XMLSchema#string

Lingfeng Qin

http://www.w3.org/2001/XMLSchema#string

Qingle Li

http://www.w3.org/2001/XMLSchema#string

Rahmat Ali

http://www.w3.org/2001/XMLSchema#string

Richard W Kim

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in myosin light chain kinase cause familial aortic dissections

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

Long term stabilization of expanding aortic aneurysms by a short course of cyclosporine A through transforming growth factor-beta induction

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

A global double-fluorescent Cre reporter mouse

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

P304

755-767

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI69942

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

124

http://www.w3.org/2001/XMLSchema#string

P50

Stefan Offermanns

P577

2014-01-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

24401272

http://www.w3.org/2001/XMLSchema#string

P921

P932

3904608

http://www.w3.org/2001/XMLSchema#string