Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1. - Wikidata - wikimedia - TriplyDB

Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1.

Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1.

http://www.wikidata.org/entity/Q37526130

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The Role of Omega-3 Polyunsaturated Fatty Acids in Stroke Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic Derivatives Dietary supplementation with omega-3 polyunsaturated fatty acids robustly promotes neurovascular restorative dynamics and improves neurological functions after stroke.Argon protects against hypoxic-ischemic brain injury in neonatal rats through activation of nuclear factor (erythroid-derived 2)-like 2 Biliverdin administration ameliorates cerebral ischemia reperfusion injury in rats and is associated with proinflammatory factor downregulation.Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke.Cleaning up after ICH: the role of Nrf2 in modulating microglia function and hematoma clearance Galectin-1-secreting neural stem cells elicit long-term neuroprotection against ischemic brain injury Intranasal Delivery of Granulocyte Colony-Stimulating Factor Enhances Its Neuroprotective Effects Against Ischemic Brain Injury in Rats.Protection against Oxygen-Glucose Deprivation/Reperfusion Injury in Cortical Neurons by Combining Omega-3 Polyunsaturated Acid with Lyciumbarbarum Polysaccharide Omega-3 polyunsaturated fatty acids mitigate blood-brain barrier disruption after hypoxic-ischemic brain injury.Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats.Anti-oxidative aspect of inhaled anesthetic gases against acute brain injury The Deleterious Effects of Oxidative and Nitrosative Stress on Palmitoylation, Membrane Lipid Rafts and Lipid-Based Cellular Signalling: New Drug Targets in Neuroimmune Disorders.Nrf2-a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke.Preventive and protective roles of dietary Nrf2 activators against central nervous system diseases.The ω-3 fatty acid α-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPARα and oxidation to oxylipins.Edaravone attenuates brain damage in rats after acute CO poisoning through inhibiting apoptosis and oxidative stress.The protective effect of activating Nrf2 / HO-1 signaling pathway on cardiomyocyte apoptosis after coronary microembolization in rats.Purine receptors are required for DHA-mediated neuroprotection against oxygen and glucose deprivation in hippocampal slices.mfat-1 transgene protects cultured adult neural stem cells against cobalt chloride-mediated hypoxic injury by activating Nrf2/ARE pathways.S-allyl cysteine activates the Nrf2-dependent antioxidant response and protects neurons against ischemic injury in vitro and in vivo.Circulating long-chain n-3 polyunsaturated fatty acid and incidence of stroke: a meta-analysis of prospective cohort studies.A Post-stroke Therapeutic Regimen with Omega-3 Polyunsaturated Fatty Acids that Promotes White Matter Integrity and Beneficial Microglial Responses after Cerebral Ischemia.Delayed Docosahexaenoic Acid Treatment Combined with Dietary Supplementation of Omega-3 Fatty Acids Promotes Long-Term Neurovascular Restoration After Ischemic Stroke.Advanced neuroprotection for brain ischemia: an alternative approach to minimize stroke damage.Posttreatment with 11-Keto-β-Boswellic Acid Ameliorates Cerebral Ischemia-Reperfusion Injury: Nrf2/HO-1 Pathway as a Potential Mechanism.Long-chain omega-3 fatty acids in aneurysmal subarachnoid hemorrhage: A randomized pilot trial of pharmaconutrition.Docosahexaenoic Acid Induces Expression of Heme Oxygenase-1 and NAD(P)H:quinone Oxidoreductase through Activation of Nrf2 in Human Mammary Epithelial Cells.Glycerophospholipid Supplementation as a Potential Intervention for Supporting Cerebral Structure in Older Adults.Curative effect of sesame oil in a rat model of chronic kidney disease.Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation.Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice.Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction.Unveiling anti-oxidative and anti-inflammatory effects of docosahexaenoic acid and its lipid peroxidation product on lipopolysaccharide-stimulated BV-2 microglial cells.

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Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1.

http://www.wikidata.org/entity/Q37526130

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JNEUROSCI.4043-13.2014

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Journal of Neuroscience

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Omega-3 fatty acids protect th ...... upregulating heme oxygenase 1.

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Baoliang Sun

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Feng Zhang

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Guodong Cao

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Jun Chen

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Leilei Mao

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Meijuan Zhang

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Suping Wang

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Wenting Zhang

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Xiaoming Hu

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Yanqin Gao

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P2860

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

Transduction of redox signaling by electrophile-protein reactions

Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals.

Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse.

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10.1523/JNEUROSCI.4043-13.2014

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