In vitro mutagenesis of the v-sis transforming gene defines functional domains of its growth factor-related product.

In vitro mutagenesis of the v-sis transforming gene defines functional domains of its growth factor-related product.

Item
http://www.wikidata.org/entity/Q37527552
Two PDGF-B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activationStructural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteinsPDGF in gliomas: more than just a growth factor?Cell surface expression of membrane-anchored v-sis gene products: glycosylation is not required for cell surface transportIntracellular retention of membrane-anchored v-sis protein abrogates autocrine signal transductionA small v-sis/platelet-derived growth factor (PDGF) B-protein domain in which subtle conformational changes abrogate PDGF receptor interaction and transforming activity.Immunochemical localization of the epitope for a monoclonal antibody that neutralizes human platelet-derived growth factor mitogenic activityIdentification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factorDeletions in the N-terminal coding region of the v-sis gene: determination of the minimal transforming regionDeletions in the C-terminal coding region of the v-sis gene: dimerization is required for transformation.Genetic organization of the c-sis transcription unit.The phenotypic characteristics of simian sarcoma virus-transformed human fibroblasts suggest that the v-sis gene product acts solely as a PDGF receptor agonist in cell transformation.
P2860

In vitro mutagenesis of the v-sis transforming gene defines functional domains of its growth factor-related product.

Item
http://www.wikidata.org/entity/Q37527552
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
In vitro mutagenesis of the v- ...... growth factor-related product.
@en
In vitro mutagenesis of the v- ...... growth factor-related product.
@nl
type
label
In vitro mutagenesis of the v- ...... growth factor-related product.
@en
In vitro mutagenesis of the v- ...... growth factor-related product.
@nl
prefLabel
In vitro mutagenesis of the v- ...... growth factor-related product.
@en
In vitro mutagenesis of the v- ...... growth factor-related product.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
In vitro mutagenesis of the v- ...... growth factor-related product.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932