Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. - Wikidata - wikimedia - TriplyDB

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

http://www.wikidata.org/entity/Q37528252

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New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics Emerging role of Hippo pathway in gastric and other gastrointestinal cancers Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Targeting Mechanotransduction at the Transcriptional Level: YAP and BRD4 Are Novel Therapeutic Targets for the Reversal of Liver Fibrosis YAP and TAZ: a nexus for Hippo signaling and beyond Comparative Gene Expression Profiling of Primary and Metastatic Renal Cell Carcinoma Stem Cell-Like Cancer Cells The Hippo pathway in disease and therapy: cancer and beyond Dynamic regulation of Schwann cell enhancers after peripheral nerve injury Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.HDAC9 promotes glioblastoma growth via TAZ-mediated EGFR pathway activation.The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27Kip1.NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.Differential Sox10 genomic occupancy in myelinating glia.Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer.Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer.Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer.Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis.Tead1 regulates the expression of Peripheral Myelin Protein 22 during Schwann cell development.Targeting αvβ3 and αvβ5 integrins inhibits pulmonary metastasis in an intratibial xenograft osteosarcoma mouse model.Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma.Molecular insights into NF2/Merlin tumor suppressor function.The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.Cellular Organization and Cytoskeletal Regulation of the Hippo Signaling Network.YAP/TAZ at the Roots of Cancer.Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression.Arhgef7 promotes activation of the Hippo pathway core kinase Lats YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression.Targeting the Hippo signalling pathway for cancer treatment.Integrins and Cell Metabolism: An Intimate Relationship Impacting Cancer.Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway.HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension.NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors.Platelets reduce anoikis and promote metastasis by activating YAP1 signaling.NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart.Mapping the STK4/Hippo signaling network in prostate cancer cell.Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells.TIMAP, the versatile protein phosphatase 1 regulator in endothelial cells.

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Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

http://www.wikidata.org/entity/Q37528252

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on January 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

@en

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

@nl

type

label

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

@en

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

@nl

prefLabel

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

@en

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

@nl

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Nature Communications

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Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase

@en

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Frances Lock

http://www.w3.org/2001/XMLSchema#string

Isabel Serrano

http://www.w3.org/2001/XMLSchema#string

Paul C McDonald

http://www.w3.org/2001/XMLSchema#string

William J Muller

http://www.w3.org/2001/XMLSchema#string

P2860

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

Integrin-linked kinase phosphorylates the myosin phosphatase target subunit at the inhibitory site in platelet cytoskeleton

The hippo signaling pathway in development and cancer

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2976

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scholarly article

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10.1038/NCOMMS3976

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4

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2013-01-01T00:00:00Z

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259394380

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24356468

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3905719

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