Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
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New Perspectives on DNA and RNA Triplexes As Effectors of Biological ActivityMethods to detect replication-dependent and replication-independent DNA structure-induced genetic instabilityThe hidden side of unstable DNA repeats: Mutagenesis at a distanceHuman DHX9 helicase unwinds triple-helical DNA structuresDHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cellsHuman replication protein A melts a DNA triple helix structure in a potent and specific mannerDisease-causing 7.4 kb cis-regulatory deletion disrupting conserved non-coding sequences and their interaction with the FOXL2 promotor: implications for mutation screening.Alternative DNA structure formation in the mutagenic human c-MYC promoter.Triple helix-interacting proteins and cancer.Molecular analyses of DNA helicases involved in the replicational stress response.Triplex technology in studies of DNA damage, DNA repair, and mutagenesisWhat does physics have to do with cancer?Telomeric repeat mutagenicity in human somatic cells is modulated by repeat orientation and G-quadruplex stability.Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract.Non-B DNA structure-induced genetic instability and evolution.Z-DNA-forming sequences generate large-scale deletions in mammalian cells.Potential non-B DNA regions in the human genome are associated with higher rates of nucleotide mutation and expression variation.Long homopurine*homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region.Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells.Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae.Replication fork regression in repetitive DNAs.Double-strand breaks in the myotonic dystrophy type 1 and the fragile X syndrome triplet repeat sequences induce different types of mutations in DNA flanking sequences in Escherichia coli.Genetic variation in human DNA replication timingOn the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Priming DNA replication from triple helix oligonucleotides: possible threestranded DNA in DNA polymerases.Repeat instability during DNA repair: Insights from model systemsTranscription blockage by stable H-DNA analogs in vitro.Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.Intrastrand triplex DNA repeats in bacteria: a source of genomic instability.Naturally extended CT . AG repeats increase H-DNA structures and promoter activity in the smooth muscle myosin light chain kinase geneTriplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer.Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.Inhibitory effect of a short Z-DNA forming sequence on transcription elongation by T7 RNA polymerase.DNA triple helices: biological consequences and therapeutic potential.Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequencesDNA structure-induced genomic instability in vivo.FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange.RecQ and RecG helicases have distinct roles in maintaining the stability of polypurine.polypyrimidine sequences.Methods to determine DNA structural alterations and genetic instability.XPD-dependent activation of apoptosis in response to triplex-induced DNA damage.
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P2860
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on September 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
@en
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
@nl
type
label
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
@en
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
@nl
prefLabel
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
@en
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
@nl
P2860
P356
P1476
Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.
@en
P2093
Guliang Wang
Karen M Vasquez
P2860
P304
13448-13453
P356
10.1073/PNAS.0405116101
P407
P577
2004-09-01T00:00:00Z