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Listeria-based cancer vaccines that segregate immunogenicity from toxicity

Listeria-based cancer vaccines that segregate immunogenicity from toxicity

http://www.wikidata.org/entity/Q37535306

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Mesothelin targeted cancer immunotherapy Vaccines for pancreatic cancer Antigen-specific immunotherapy of cervical and ovarian cancer Nonviral oncogenic antigens and the inflammatory signals driving early cancer development as targets for cancer immunoprevention Interplay between CD8α+ dendritic cells and monocytes in response to Listeria monocytogenes infection attenuates T cell responses The intestinal microbiome and surgical disease.Attenuated Listeria monocytogenes: a powerful and versatile vector for the future of tumor immunotherapy.A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.Suppression of autoimmune demyelinating disease by preferential stimulation of CNS-specific CD8 T cells using Listeria-encoded neuroantigen.An anti-vascular endothelial growth factor receptor 2/fetal liver kinase-1 Listeria monocytogenes anti-angiogenesis cancer vaccine for the treatment of primary and metastatic Her-2/neu+ breast tumors in a mouse model.Mesothelin Immunotherapy for Cancer: Ready for Prime Time?A Listeria monocytogenes-based vaccine that secretes sand fly salivary protein LJM11 confers long-term protection against vector-transmitted Leishmania major.Radiation therapy combined with Listeria monocytogenes-based cancer vaccine synergize to enhance tumor control in the B16 melanoma model Attenuated Listeria monocytogenes reprograms M2-polarized tumor-associated macrophages in ovarian cancer leading to iNOS-mediated tumor cell lysis.Conditional lethality yields a new vaccine strain of Listeria monocytogenes for the induction of cell-mediated immunity Pathogenicity and immunogenicity of a vaccine strain of Listeria monocytogenes that relies on a suicide plasmid to supply an essential gene product.Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional tolerance Glycolipid antigens for treating hepatic colorectal cancer metastases and their effect on the therapeutic efficacy of live attenuated Listeria monocytogenes Yogi Berra, Forrest Gump, and the discovery of Listeria actin comet tails.Investigational approaches for mesothelioma.Dendritic-cell-based therapeutic cancer vaccines Rhamnose-inducible gene expression in Listeria monocytogenes.Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns.A live attenuated Listeria monocytogenes vaccine vector expressing SIV Gag is safe and immunogenic in macaques and can be administered repeatedly.Directed antigen delivery as a vaccine strategy for an intracellular bacterial pathogen.Comparison of different live vaccine strategies in vivo for delivery of protein antigen or antigen-encoding DNA and mRNA by virulence-attenuated Listeria monocytogenes Listeria-based vaccines can overcome tolerance by expanding low avidity CD8+ T cells capable of eradicating a solid tumor in a transgenic mouse model of cancer.Attenuated Listeria monocytogenes vaccine vectors expressing influenza A nucleoprotein: preclinical evaluation and oral inoculation of volunteers.Attenuated Listeria monocytogenes vectors overcome suppressive plasma factors during HIV infection to stimulate myeloid dendritic cells to promote adaptive immunity and reactivation of latent virus.The peripheral myeloid expansion driven by murine cancer progression is reversed by radiation therapy of the tumor Vaginal protection and immunity after oral immunization of mice with a novel vaccine strain of Listeria monocytogenes expressing human immunodeficiency virus type 1 gag.Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA.Live bacterial vaccine vectors: an overview.Virological and preclinical characterization of a dendritic cell targeting, integration-deficient lentiviral vector for cancer immunotherapy Inflammasome-mediated inhibition of Listeria monocytogenes-stimulated immunity is independent of myelomonocytic function STING-dependent type I IFN production inhibits cell-mediated immunity to Listeria monocytogenes.Absence of vasoactive intestinal peptide expression in hematopoietic cells enhances Th1 polarization and antiviral immunity in mice A novel model for IFN-γ-mediated autoinflammatory syndromes.Cytosolic entry controls CD8+-T-cell potency during bacterial infection.Safety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer.

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Listeria-based cancer vaccines that segregate immunogenicity from toxicity

http://www.wikidata.org/entity/Q37535306

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 13 September 2004

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Listeria-based cancer vaccines that segregate immunogenicity from toxicity

@en

Listeria-based cancer vaccines that segregate immunogenicity from toxicity.

@nl

type

label

Listeria-based cancer vaccines that segregate immunogenicity from toxicity

@en

Listeria-based cancer vaccines that segregate immunogenicity from toxicity.

@nl

prefLabel

Listeria-based cancer vaccines that segregate immunogenicity from toxicity

@en

Listeria-based cancer vaccines that segregate immunogenicity from toxicity.

@nl

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PNAS.0406035101

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Listeria-based cancer vaccines that segregate immunogenicity from toxicity

@en

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Daniel A Portnoy

http://www.w3.org/2001/XMLSchema#string

David N Cook

http://www.w3.org/2001/XMLSchema#string

Dirk G Brockstedt

http://www.w3.org/2001/XMLSchema#string

Keith S Bahjat

http://www.w3.org/2001/XMLSchema#string

Martin A Giedlin

http://www.w3.org/2001/XMLSchema#string

Meredith L Leong

http://www.w3.org/2001/XMLSchema#string

Thomas W Dubensky

http://www.w3.org/2001/XMLSchema#string

Weiqun Liu

http://www.w3.org/2001/XMLSchema#string

William Luckett

http://www.w3.org/2001/XMLSchema#string

Yi Gao

http://www.w3.org/2001/XMLSchema#string

P2860

Entry of Listeria monocytogenes into neurons occurs by cell-to-cell spread: an in vitro study

Dissemination of Listeria monocytogenes by infected phagocytes.

The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product

A novel approach of direct ex vivo epitope mapping identifies dominant and subdominant CD4 and CD8 T cell epitopes from Listeria monocytogenes.

A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes.

Innate recognition of bacteria by a macrophage cytosolic surveillance pathway

Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions.

Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors.

Delivery of a viral antigen to the class I processing and presentation pathway by Listeria monocytogenes.

Effector and memory T-cell differentiation: implications for vaccine development.

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13832-13837

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scholarly article

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10.1073/PNAS.0406035101

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P433

38

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101

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2004-09-13T00:00:00Z

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8349894

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15365184

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518841

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