Application of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug-Drug Interaction with Antidepressants

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Application of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug-Drug Interaction with Antidepressants

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article científic

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article scientifique

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bilimsel makale

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scientific article published on 18 October 2016

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vedecký článok

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vetenskaplig artikel

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Application of Mice Humanized ...... teraction with Antidepressants

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Application of Mice Humanized ...... eraction with Antidepressants.

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Application of Mice Humanized ...... teraction with Antidepressants

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Application of Mice Humanized ...... eraction with Antidepressants.

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Application of Mice Humanized ...... teraction with Antidepressants

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Application of Mice Humanized ...... eraction with Antidepressants.

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P1476

Application of Mice Humanized ...... teraction with Antidepressants

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P2093

A Kenneth MacLeod

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Colin J Henderson

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P2860

O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants

Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study

Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen

Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates.

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.

Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes.

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry.

Pharmacogenetics of cytochrome p4502D6: genetic background and clinical implication.

Breast cancer recurrence risk in relation to antidepressant use after diagnosis.

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17-22

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scholarly article

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10.1124/DMD.116.073437

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Colin J Henderson

C R Wolf

P577

2016-10-18T00:00:00Z

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27756789

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5193068

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