Inactivation of Capicua drives cancer metastasis - Wikidata - wikimedia - TriplyDB

Inactivation of Capicua drives cancer metastasis

Inactivation of Capicua drives cancer metastasis

http://www.wikidata.org/entity/Q37541479

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Dynamics of chromatin accessibility during TGF-β-induced EMT of Ras-transformed mammary gland epithelial cells.Whole-Genome Sequence of the Metastatic PC3 and LNCaP Human Prostate Cancer Cell Lines.Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascade Generation of novel patient-derived CIC- DUX4 sarcoma xenografts and cell lines.Cofilin 1 induces the epithelial-mesenchymal transition of gastric cancer cells by promoting cytoskeletal rearrangement.A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer.Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression.CIC break-apart fluorescence in-situ hybridization misses a subset of CIC-DUX4 sarcomas: a clinicopathological and molecular study.Parallel imaging of Drosophila embryos for quantitative analysis of genetic perturbations of the Ras pathway.ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation.Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.Metastasis: From head to tail.A double-edged sword: The world according to Capicua in cancer.ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1.Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity.Capicua controls Toll/IL-1 signaling targets independently of RTK regulation.Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication.The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer.The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation

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Inactivation of Capicua drives cancer metastasis

http://www.wikidata.org/entity/Q37541479

description

2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

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2016年學術文章

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name

Inactivation of Capicua drives cancer metastasis

@en

Inactivation of Capicua drives cancer metastasis.

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type

label

Inactivation of Capicua drives cancer metastasis

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Inactivation of Capicua drives cancer metastasis.

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prefLabel

Inactivation of Capicua drives cancer metastasis

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Inactivation of Capicua drives cancer metastasis.

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Nature Genetics

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Inactivation of Capicua drives cancer metastasis

@en

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Andrew D Simmons

http://www.w3.org/2001/XMLSchema#string

Asmin Tulpule

http://www.w3.org/2001/XMLSchema#string

Beatrice Gini

http://www.w3.org/2001/XMLSchema#string

Collin M Blakely

http://www.w3.org/2001/XMLSchema#string

Frank Breitenbuecher

http://www.w3.org/2001/XMLSchema#string

Gorjan Hrustanovic

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Henry J Haringsma

http://www.w3.org/2001/XMLSchema#string

James Suh

http://www.w3.org/2001/XMLSchema#string

Jennifer Flanagan

http://www.w3.org/2001/XMLSchema#string

Kyle Gowen

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P2860

A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling

Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair

The Cancer Genome Atlas Pan-Cancer analysis project

EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC.

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Mutations in CIC and FUBP1 contribute to human oligodendroglioma

Comprehensive molecular characterization of gastric adenocarcinoma

Comprehensive molecular profiling of lung adenocarcinoma.

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10.1038/NG.3728

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1

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49

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2016-11-21T00:00:00Z

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