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Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

http://www.wikidata.org/entity/Q37550198

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Cancer Bioinformatic Methods to Infer Meaningful Data From Small-Size Cohorts Harnessing Pandemonium: The Clinical Implications of Tumor Heterogeneity in Ovarian Cancer Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and Treatment Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis Two different, mutually exclusively distributed, TP53 mutations in ovarian and peritoneal tumor tissues of a serous ovarian cancer patient: indicative for tumor origin?A framework for genomic biomarker actionability and its use in clinical decision making Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma Preferential Allele Expression Analysis Identifies Shared Germline and Somatic Driver Genes in Advanced Ovarian Cancer.Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance.Ovarian cancer treatment: The end of empiricism?Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer.Transcriptomics in cancer diagnostics: developments in technology, clinical research and commercialization.Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer.Engineering and optimising deaminase fusions for genome editing.High-grade serous ovarian cancer: the clone wars.TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2.Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.Involvement of DPP9 in gene fusions in serous ovarian carcinoma.Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study.Ovarian Cancers: Genetic Abnormalities, Tumor Heterogeneity and Progression, Clonal Evolution and Cancer Stem Cells.Implementation of a Multicenter Biobanking Collaboration for Next-Generation Sequencing-Based Biomarker Discovery Based on Fresh Frozen Pretreatment Tumor Tissue Biopsies.Intraindividual genomic heterogeneity of high-grade serous carcinoma of the ovary and clinical utility of ascitic cancer cells for mutation profiling.Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.Genetic Evidence for Early Peritoneal Spreading in Pelvic High-Grade Serous Cancer.Tumor evolution and chemoresistance in ovarian cancer

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Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

http://www.wikidata.org/entity/Q37550198

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

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2013年學術文章

@zh-hant

name

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

@en

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer.

@nl

type

label

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

@en

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer.

@nl

prefLabel

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

@en

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer.

@nl

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Genome Research

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Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

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Clarence C Lee

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Edwin Cuppen

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Emile E Voest

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Geert A Cirkel

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Ivo Renkens

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Jennifer Kreeftmeijer

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Karen Duran

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Marco J Koudijs

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Markus J van Roosmalen

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Martijn P Lolkema

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P2860

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

The Hallmarks of Cancer

Cytoscape: a software environment for integrated models of biomolecular interaction networks

International network of cancer genome projects.

Mutational processes molding the genomes of 21 breast cancers

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Complex landscapes of somatic rearrangement in human breast cancer genomes.

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

A census of human cancer genes

Fast and accurate short read alignment with Burrows-Wheeler transform

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200-211

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10.1101/GR.161026.113

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2

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24

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Marlous Hoogstraat

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