Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107.
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A polymorphism in the OPRM1 3'-untranslated region is associated with methadone efficacy in treating opioid dependencemiR-219-5p targets CaMKIIγ to attenuate morphine tolerance in ratsInteractions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors.Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia.Morphine Promotes Astrocyte-Preferential Differentiation of Mouse Hippocampal Progenitor Cells via PKCε-Dependent ERK Activation and TRBP PhosphorylationRegulation and Functional Implications of Opioid Receptor Splicing in Opioid Pharmacology and HIV PathogenesisMicroRNAs Are Involved in the Development of Morphine-Induced Analgesic Tolerance and Regulate Functionally Relevant Changes in Serpini1.Downregulation of miR-219 enhances brain-derived neurotrophic factor production in mouse dorsal root ganglia to mediate morphine analgesic tolerance by upregulating CaMKIIγ.Identification of Circulating miRNAs Differentially Regulated by Opioid TreatmentRole of G protein-coupled receptors-microRNA interactions in gastrointestinal pathophysiology.OPRM1 Methylation Contributes to Opioid Tolerance in Cancer Patients.Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia.The Regulatory Mechanisms and Therapeutic Potential of MicroRNAs: From Chronic Pain to Morphine Tolerance.Novel Roles of Non-Coding RNAs in Opioid Signaling and Cardioprotection
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Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Morphine regulates expression ...... RM1) gene via miR-103/miR-107.
@en
Morphine regulates expression ...... RM1) gene via miR-103/miR-107.
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Morphine regulates expression ...... RM1) gene via miR-103/miR-107.
@en
Morphine regulates expression ...... RM1) gene via miR-103/miR-107.
@nl
prefLabel
Morphine regulates expression ...... RM1) gene via miR-103/miR-107.
@en
Morphine regulates expression ...... RM1) gene via miR-103/miR-107.
@nl
P2093
P2860
P356
P1476
Morphine regulates expression ...... RM1) gene via miR-103/miR-107.
@en
P2093
Gavril W Pasternak
Mingming Xu
Ying-Xian Pan
Zhigang Lu
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P304
P356
10.1124/MOL.113.089292
P577
2013-12-03T00:00:00Z