Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
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Vaccines: from empirical development to rational designLost in Translation (LiT): IUPHAR Review 6A Blueprint for HIV Vaccine DiscoveryDevelopment of humanized mouse models to study human malaria parasite infectionNew generation humanized mice for virus research: comparative aspects and future prospectsInteractions between the microbiota and the immune systemPreclinical mouse cancer models: a maze of opportunities and challenges.Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populationsTowards a small animal model for hepatitis CNew horizons for studying human hepatotropic infectionsStructural determinants of host specificity of complement Factor H recruitment by Streptococcus pneumoniaeUsing animal models to overcome temporal, spatial and combinatorial challenges in HIV persistence researchDendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sitesA topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu miceA novel mouse model for stable engraftment of a human immune system and human hepatocytesHuman CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rγ-/- (NSG) miceGeneration of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" miceHumanized mice with ectopic artificial liver tissues.Complete Plasmodium falciparum liver-stage development in liver-chimeric mice.Human allograft rejection in humanized mice: a historical perspectiveHuman-animal chimeras for vaccine development: an endangered species or opportunity for the developing world?Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model.Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routesHumanized mouse models to study human diseasesSomatic genetics empowers the mouse for modeling and interrogating developmental and disease processes.NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejectionHTLV-1 propels thymic human T cell development in "human immune system" Rag2⁻/⁻ gamma c⁻/⁻ mice.Back to the future: how human induced pluripotent stem cells will transform regenerative medicine.Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.Bone marrow transplantation concurrently reconstitutes donor liver and immune system across host species barrier in miceHIV-1 Env-specific memory and germinal center B cells in C57BL/6 miceBarriers of hepatitis C virus interspecies transmissionHumanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells.Genetic Dissection of the Host Tropism of Human-Tropic Pathogens.Expansion of activated memory CD4+ T cells affects infectivity of CCR5-tropic HIV-1 in humanized NOD/SCID/JAK3null mice.Specificity for human hemoglobin enhances Staphylococcus aureus infection.Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivoHuman IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lungEnhanced methamphetamine metabolism in rhesus macaque as compared with human: an analysis using a novel method of liquid chromatography with tandem mass spectrometry, kinetic study, and substrate docking.
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Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
@en
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
@nl
type
label
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
@en
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
@nl
prefLabel
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
@en
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
@nl
P2093
P50
P1433
P1476
Humanized mice for modeling human infectious disease: challenges, progress, and outlook
@en
P2093
Alexander Ploss
Anja U van Lent
Anthony Rongvaux
Carlos A Guzman
Charles M Rice
Chengyan Wang
Chozhavendan Rathinam
Elizabeth Eynon
Hergen Spits
Hongkui Deng
P356
10.1016/J.CHOM.2009.06.006
P50
P577
2009-07-01T00:00:00Z