Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.
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VEGF(165) mediates glomerular endothelial repairRole of PDGF B-chain and PDGF receptors in rat tubular regeneration after acute injurySmall molecule receptor tyrosine kinase inhibitor of platelet-derived growth factor signaling (SU9518) modifies radiation response in fibroblasts and endothelial cells.The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria.Afadin is localized at cell-cell contact sites in mesangial cells and regulates migratory polarity.A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF.Infusion of platelet-derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in ratsMesangial cell apoptosis: the major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritisInduction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture.An antibody reactive with domain 4 of the platelet-derived growth factor beta receptor allows BB binding while inhibiting proliferation by impairing receptor dimerization.A granulocyte inhibitory protein overexpressed in chronic renal disease regulates expression of interleukin 6 and interleukin 8.Mesangial cell proliferation inhibitors for the treatment of proliferative glomerular disease.Hydrogen peroxide-inducible clone-5 regulates mesangial cell proliferation in proliferative glomerulonephritis in miceActivation of mesangial cells by the phosphatase inhibitor vanadate. Potential implications for diabetic nephropathy.Role of interleukin-1 in mesangial cell proliferation and matrix deposition in experimental mesangioproliferative nephritisSPARC is expressed by mesangial cells in experimental mesangial proliferative nephritis and inhibits platelet-derived-growth-factor-medicated mesangial cell proliferation in vitro.Identification of platelet-derived growth factor A and B chains in human renal vascular rejectionStructural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex-mediated glomerulonephritis.The role of PDGF in radiation oncology.Quinazoline derivatives: synthesis and bioactivities.Imatinib suppresses cryoglobulinemia and secondary membranoproliferative glomerulonephritisCreation of an In vivo cytosensor using engineered mesangial cells. Automatic sensing of glomerular inflammation controls transgene activity.Platelet-derived growth factor and fibroblast growth factor differentially regulate interleukin 1beta- and cAMP-induced nitric oxide synthase expression in rat renal mesangial cells.Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo.Signal transduction in podocytes--spotlight on receptor tyrosine kinases.Biological pathways and potential targets for prevention and therapy of chronic allograft nephropathyCell biology of mesangial cells: the third cell that maintains the glomerular capillary.Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.Expression of platelet-derived growth factor receptors in normal and diseased human kidney. An immunohistochemistry and in situ hybridization study.Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase Cgamma signaling pathways.New insights into mechanisms of immune glomerular injury.Reshaping the interstitium by platelet-derived growth factor. Implications for progressive renal disease.Rat glomerular mesangial cells synthesize basic fibroblast growth factor. Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis.Progression of glomerulonephritis.High glucose concentration induces the overexpression of transforming growth factor-beta through the activation of a platelet-derived growth factor loop in human mesangial cells.Participation of glomerular endothelial cells in the capillary repair of glomerulonephritisActivation of Src kinase in platelet-derived growth factor-B-dependent tubular regeneration after acute ischemic renal injuryVisceral glomerular epithelial cells can proliferate in vivo and synthesize platelet-derived growth factor B-chain.Platelet-derived growth factor-BB induces cystathionine γ-lyase expression in rat mesangial cells via a redox-dependent mechanism.Expression of a rat PDGF receptor beta ectodomain generates a low affinity ligand antagonist.
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Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Platelet-derived growth factor ...... ferative nephritis in the rat.
@en
type
label
Platelet-derived growth factor ...... ferative nephritis in the rat.
@en
prefLabel
Platelet-derived growth factor ...... ferative nephritis in the rat.
@en
P2093
P2860
P356
P1476
Platelet-derived growth factor ...... ferative nephritis in the rat.
@en
P2093
C E Alpers
D F Bowen-Pope
P E Phillips
R G Gronwald
P2860
P304
P356
10.1073/PNAS.88.15.6560
P407
P577
1991-08-01T00:00:00Z