Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.
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Neuroprotection in Oxidative Stress-Related Neurodegenerative Diseases: Role of Endocannabinoid System Modulation.Circulating Endocannabinoids: From Whence Do They Come and Where are They Going?Chemical tools to modulate 2-arachidonoylglycerol biosynthesis.Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage.Anti-nociceptive interactions between opioids and a cannabinoid receptor 2 agonist in inflammatory pain.Cannabinoid CB1 and CB2 Receptor Signaling and BiasTargeting Cannabinoid Signaling in the Immune System: "High"-ly Exciting Questions, Possibilities, and Challenges.Overactive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve.Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference.Frontiers in Medicinal Chemistry 2017 in Bern, Switzerland.Why support a separate medical access framework for cannabis?Selective cannabinoid 2 receptor stimulation reduces tubular epithelial cell damage following renal ischemia-reperfusion injury.Perinatal maternal high-fat diet induces early obesity and sex-specific alterations of the endocannabinoid system in white and brown adipose tissue of weanling rat offspring.Retromer stops beta-arrestin 1-mediated signaling from internalized cannabinoid 2 receptors.Synergistic interaction of the cannabinoid and death receptor systems - a potential target for future cancer therapies?CB1 and CB2 Receptor Pharmacology.Cannabinoid Receptor-2 Ameliorates Inflammation in Murine Model of Crohn's Disease.Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells.Development of Highly Affine and Selective Fluorinated Cannabinoid Type 2 Receptor Ligands.The Endocannabinoid Reuptake Inhibitor WOBE437 Is Orally Bioavailable and Exerts Indirect Polypharmacological Effects via Different Endocannabinoid Receptors.Identification of Putative Precursor Genes for the Biosynthesis of Cannabinoid-Like Compound in Radula marginata.Development of a Cannabinoid-Based Photoaffinity Probe to Determine the Δ8/9-Tetrahydrocannabinol Protein Interaction Landscape in Neuroblastoma Cells.Maternal high-fat diet consumption induces sex-dependent alterations of the endocannabinoid system and redox homeostasis in liver of adult rat offspring
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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 January 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cannabinoid CB2 receptor ligan ...... lling and off-target activity.
@en
Cannabinoid CB2 receptor ligan ...... lling and off-target activity.
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type
label
Cannabinoid CB2 receptor ligan ...... lling and off-target activity.
@en
Cannabinoid CB2 receptor ligan ...... lling and off-target activity.
@nl
prefLabel
Cannabinoid CB2 receptor ligan ...... lling and off-target activity.
@en
Cannabinoid CB2 receptor ligan ...... lling and off-target activity.
@nl
P2093
P2860
P50
P921
P356
P1476
Cannabinoid CB2 receptor ligan ...... alling and off-target activity
@en
P2093
Aron H Lichtman
Benno Rothenhäusler
Camille Perret
Christa MacDonald
Christoph Ullmer
Elliot D Mock
Filomena Fezza
Henk de Vries
Jürg Gertsch
P2860
P2888
P356
10.1038/NCOMMS13958
P407
P50
P577
2017-01-03T00:00:00Z