Platelet-derived growth factor: mechanism of action and possible in vivo function.
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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunitIdentification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gammaIdentification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinasesVascular endothelial growth factor B, a novel growth factor for endothelial cellsA novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domainsPhosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivoStructural and functional studies on platelet-derived growth factorThe extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptorsTyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activationProliferative vitreoretinopathy: current and emerging treatmentsRenal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in ratsPDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularlyPeptide gene expression in gastrointestinal mucosal ulceration: ordered sequence or redundancy?Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis.The distribution of PDGFs and PDGF-receptors during murine secondary palate development.Role of receptor tyrosine kinases and their ligands in glioblastoma.Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans.Autocrine ligand binding to cell receptors. Mathematical analysis of competition by solution "decoys".Taxol inhibits neointimal smooth muscle cell accumulation after angioplasty in the ratRETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class.Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signalingAssessment of tracer 99mTc(V)-DMSA uptake as a measure of tumor cell proliferation in vitro.Association of platelet-derived growth factor-B chain with simian human immunodeficiency virus encephalitis.Prognostic value of platelet derived growth factor alpha receptor expression in grade 2 astrocytomas and oligoastrocytomas.Platelet-derived growth factor alpha receptor gene expression: isolation and characterization of the promoter and upstream regulatory elementsUpregulated β1-6 branch N-glycan marks early gliomagenesis but exhibited biphasic expression in the progression of astrocytic glioma.Platelet-derived growth factor-A-induced retinal gliosis protects against ischemic retinopathy.Tumor cell and connective tissue cell interactions in human colorectal adenocarcinoma. Transfer of platelet-derived growth factor-AB/BB to stromal cellsDecreased expression of Ras GTPase activating protein in human trophoblastic tumors.Photoreceptor-specific expression of platelet-derived growth factor-B results in traction retinal detachmentRous-Whipple Award Lecture. Atherosclerosis: a defense mechanism gone awry.Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta.A specific combination of substrates is involved in signal transduction by the kit-encoded receptor.The effect of platelet derived growth factor-AB on periodontal ligament fibroblasts: An in vitro studyPlatelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BBPlatelet-Lymphocyte Ratio as a Useful Predictor of the Therapeutic Effect of Neoadjuvant Chemotherapy in Breast CancerDecreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices.Beta-actin mRNA localization is regulated by signal transduction mechanisms.Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action.Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively
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P2860
Platelet-derived growth factor: mechanism of action and possible in vivo function.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Platelet-derived growth factor: mechanism of action and possible in vivo function.
@en
Platelet-derived growth factor: mechanism of action and possible in vivo function.
@nl
type
label
Platelet-derived growth factor: mechanism of action and possible in vivo function.
@en
Platelet-derived growth factor: mechanism of action and possible in vivo function.
@nl
prefLabel
Platelet-derived growth factor: mechanism of action and possible in vivo function.
@en
Platelet-derived growth factor: mechanism of action and possible in vivo function.
@nl
P2860
P356
P1476
Platelet-derived growth factor: mechanism of action and possible in vivo function.
@en
P2093
P2860
P304
P356
10.1091/MBC.1.8.555
P577
1990-07-01T00:00:00Z