In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission
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Is wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activityEfficacy of Carraguard-based microbicides in vivo despite variable in vitro activityDendrimers as tunable vectors of drug delivery systems and biomedical and ocular applicationsIn vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicideEfficacy, stability, and biosafety of sifuvirtide gel as a microbicide candidate against HIV-1SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humansA phase I randomized placebo controlled trial of the safety of 3% SPL7013 Gel (VivaGel®) in healthy young women administered twice daily for 14 daysStructure activity relationship of dendrimer microbicides with dual action antiviral activityCandidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants.Overview of microbicides for the prevention of human immunodeficiency virus.Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro.Combinations of 3-hydroxyphthalic anhydride-modified ovalbumin with antiretroviral drug-based microbicide candidates display synergistic and complementary effects against HIV-1 infection.Synthesis, structure and molecular modelling of anionic carbosilane dendrimers.Antibacterial activities of poly(amidoamine) dendrimers terminated with amino and poly(ethylene glycol) groupsAnti-HIV agents targeting the interaction of gp120 with the cellular CD4 receptor.Role of seminal plasma in the anti-HIV-1 activity of candidate microbicides.Candidate polyanionic microbicides inhibit human T-cell lymphotropic virus type 1 receptor interactions, cell-free infection, and cell-cell spread.Advances in the Development of Microbicides for the Prevention of HIV Infection.Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection3-hydroxyphthalic anhydride-modified chicken ovalbumin exhibits potent and broad anti-HIV-1 activity: a potential microbicide for preventing sexual transmission of HIV-1Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safetyMaleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission.Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action.PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture.Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infectionIn vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides.In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories.Use of human mucosal tissue to study HIV-1 pathogenesis and evaluate HIV-1 prevention modalities.In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate modelFemale genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections.Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1.Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product.Peptide-derivatized SB105-A10 dendrimer inhibits the infectivity of R5 and X4 HIV-1 strains in primary PBMCs and cervicovaginal histoculturesVirucidal activity of the dendrimer microbicide SPL7013 against HIV-1.Non-specific microbicide product development: then and nowPreclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.Effect of topical microbicides on infectious human immunodeficiency virus type 1 binding to epithelial cellsMolecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infectionsCharacterization of UC781-tenofovir combination gel products for HIV-1 infection prevention in an ex vivo ectocervical model.
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In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
In vitro comparison of topical ...... ency virus type 1 transmission
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In vitro comparison of topical ...... ncy virus type 1 transmission.
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type
label
In vitro comparison of topical ...... ency virus type 1 transmission
@en
In vitro comparison of topical ...... ncy virus type 1 transmission.
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prefLabel
In vitro comparison of topical ...... ency virus type 1 transmission
@en
In vitro comparison of topical ...... ncy virus type 1 transmission.
@nl
P2093
P2860
P1476
In vitro comparison of topical ...... ency virus type 1 transmission
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P2093
Aladin Siddig
Artur Ramos
Charlene S Dezzutti
Clyde E Hart
Lisa A Grohskopf
Lynn Paxton
Shambavi Subbarao
Sharon T Sullivan
Timothy J Bush
V Nicole James
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P304
P356
10.1128/AAC.48.10.3834-3844.2004
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P577
2004-10-01T00:00:00Z