Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth.
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ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway.New insights into redox homeostasis as a therapeutic target in B-cell malignancies.The early metabolomic response of adipose tissue during acute cold exposure in mice.Metabolomic signature of brain cancer.Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine.Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.Farnesyl phenolic enantiomers as natural MTH1 inhibitors from Ganoderma sinense.NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway.Cypermethrin Activates Autophagosome Formation Albeit Inhibits Autophagy Owing to Poor Lysosome Quality: Relevance to Parkinson's Disease.International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H2S Levels: H2S Donors and H2S Biosynthesis Inhibitors.How do we fit ferroptosis in the family of regulated cell death?Extracellular redox state shift: A novel approach to target prostate cancer invasion.Curcumin targets multiple enzymes involved in the ROS metabolic pathway to suppress tumor cell growth.The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code.Regulation of redox balance in cancer and T cells.Cysteine Metabolism in Neuronal Redox Homeostasis.A Novel EphA2 Inhibitor Exerts Beneficial Effects in PI-IBS in Vivo and in Vitro Models via Nrf2 and NF-κB Signaling Pathways.Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism.Pushing the Limits of Cancer Therapy: The Nutrient Game.Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastomaNuclear lactate dehydrogenase A senses ROS to produce α-hydroxybutyrate for HPV-induced cervical tumor growthCan drug repurposing stop "chase and run" between aldehydes and reactive sulfur species in anti-cancer therapy?A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis
P2860
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P2860
Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Systemic depletion of L-cyst
@nl
Systemic depletion of L-cyst(e ...... s and suppresses tumor growth.
@en
type
label
Systemic depletion of L-cyst
@nl
Systemic depletion of L-cyst(e ...... s and suppresses tumor growth.
@en
prefLabel
Systemic depletion of L-cyst
@nl
Systemic depletion of L-cyst(e ...... s and suppresses tumor growth.
@en
P2093
P2860
P356
P1433
P1476
Systemic depletion of L-cyst(e ...... s and suppresses tumor growth.
@en
P2093
Achinto Saha
Candice Lamb
Everett Stone
George Georgiou
Jinyun Liu
John DiGiovanni
Kendra Triplett
Peng Huang
Scott Rowlinson
Shira L Cramer
P2860
P2888
P304
P356
10.1038/NM.4232
P407
P577
2016-11-21T00:00:00Z