Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging.
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Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesNew insights into the role of mitochondria in aging: mitochondrial dynamics and moreThe cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunctionThe crucial impact of lysosomes in aging and longevityThe many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapyMitochondrial involvement and impact in aging skeletal muscleSchisandrin B as a hormetic agent for preventing age-related neurodegenerative diseasesAutophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degenerationAutophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?Autophagy in plasma cell pathophysiologyMitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trialsMelatonin as a Potential Agent in the Treatment of SarcopeniaMelatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular DegenerationOxidative stress and the homeodynamics of iron metabolismBioanalysis of eukaryotic organellesMitochondria and oxidative stress in heart agingAging-induced proteostatic changes in the rat hippocampus identify ARP3, NEB2 and BRAG2 as a molecular circuitry for cognitive impairmentNicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.RAB26 coordinates lysosome traffic and mitochondrial localization.Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing.Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway.Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac AgeingQuantifiable biomarkers of normal aging in the Japanese medaka fish (Oryzias latipes).Enhanced retinal insulin receptor-activated neuroprotective survival signal in mice lacking the protein-tyrosine phosphatase-1B gene.Conserved and species-specific molecular denominators in mammalian skeletal muscle aging.Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue.The effects of age and muscle contraction on AMPK activity and heterotrimer composition.Rapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation.Heart failure with preserved ejection fraction: molecular pathways of the aging myocardiumPompe disease: from pathophysiology to therapy and back againSterol regulatory element-binding protein (SREBP)-1-mediated lipogenesis is involved in cell senescence.Pathological aspects of lipid peroxidation.Stem cells and neuroprotection: understanding the players.Natural compounds and aging: between autophagy and inflammasome.Proteomic identification of cathepsin B and nucleophosmin as novel UVA-targets in human skin fibroblastsThe Sick and the Weak: Neuropathies/Myopathies in the Critically Ill.Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity.Lipofuscin in human glaucomatous optic nerves.Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cellsAutofluorescence properties of murine embryonic stem cells during spontaneous differentiation phases.
P2860
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P2860
Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mitochondrial turnover and agi ...... ysosomal axis theory of aging.
@en
Mitochondrial turnover and agi ...... ysosomal axis theory of aging.
@nl
type
label
Mitochondrial turnover and agi ...... ysosomal axis theory of aging.
@en
Mitochondrial turnover and agi ...... ysosomal axis theory of aging.
@nl
prefLabel
Mitochondrial turnover and agi ...... ysosomal axis theory of aging.
@en
Mitochondrial turnover and agi ...... ysosomal axis theory of aging.
@nl
P2093
P2860
P356
P1476
Mitochondrial turnover and agi ...... ysosomal axis theory of aging.
@en
P2093
Alexei Terman
Edgar A Arriaga
Marian Navratil
Ulf T Brunk
P2860
P304
P356
10.1089/ARS.2009.2598
P577
2010-04-01T00:00:00Z