A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects.
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Epigenetics and agingMitophagy plays a central role in mitochondrial ageingHypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related DiseasesEpigenetics of Aging and Alzheimer's Disease: Implications for Pharmacogenomics and Drug ResponseEnvironmental Impact on DNA Methylation in the Germline: State of the Art and Gaps of KnowledgeDNA methylation and healthy human agingDefining the toxicology of agingIntegrative Analysis of Multi-omics Data for Discovery and Functional Studies of Complex Human Diseases.Alcohol induces cell proliferation via hypermethylation of ADHFE1 in colorectal cancer cells.Epigenetics: Linking Nutrition to Molecular Mechanisms in Aging.WI-38 senescence is associated with global and site-specific hypomethylation.The Influences of Genetic and Environmental Factors on Methylome-wide Association Studies for Human Diseases.Influence of environmental exposure on human epigenetic regulationDiscordance of DNA methylation variance between two accessible human tissues.Human leukocyte telomere length is associated with DNA methylation levels in multiple subtelomeric and imprinted lociReplicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sitesAgeing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.Concordant and discordant DNA methylation signatures of aging in human blood and brain.Epigenetic Aging Signatures Are Coherently Modified in CancerEvaluation of Methyl-Binding Domain Based Enrichment Approaches Revisited.DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry.Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol UseAging-associated DNA methylation changes in middle-aged individuals: the Young Finns study.Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human aging.Bioinformatics Methods and Tools to Advance Clinical Care. Findings from the Yearbook 2015 Section on Bioinformatics and Translational InformaticsIdentification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemiaHigh density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fractionGenome-Wide Epigenetic Studies in Human Disease: A Primer on -Omic TechnologiesEpigenetic Mechanisms of the Aging Human Retina.Methylation of Apoptosis-Associated Speck-Like Protein With a Caspase Recruitment Domain and Outcomes in Heart Failure.A Whole Methylome CpG-SNP Association Study of Psychosis in Blood and Brain TissueAge-related accrual of methylomic variability is linked to fundamental ageing mechanisms.Novel regional age-associated DNA methylation changes within human common disease-associated lociIntra-individual changes in DNA methylation not mediated by cell-type composition are correlated with aging during childhood.Ischemic stroke patients are biologically older than their chronological age.Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging.PIM1 induces cellular senescence through phosphorylation of UHRF1 at Ser311.Age-associated DNA methylation changes in naive CD4+ T cells suggest an evolving autoimmune epigenotype in aging T cells.DNA methylation dynamics in cellular commitment and differentiation.Aging, inflammation, immunity and periodontal disease.
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A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A methylome-wide study of agin ...... om blood in over 700 subjects.
@en
A methylome-wide study of agin ...... om blood in over 700 subjects.
@nl
type
label
A methylome-wide study of agin ...... om blood in over 700 subjects.
@en
A methylome-wide study of agin ...... om blood in over 700 subjects.
@nl
prefLabel
A methylome-wide study of agin ...... om blood in over 700 subjects.
@en
A methylome-wide study of agin ...... om blood in over 700 subjects.
@nl
P2093
P2860
P50
P356
P1476
A methylome-wide study of agin ...... om blood in over 700 subjects.
@en
P2093
Aki Harada
Alexandra D Hudson
Edwin J C G Van Den Oord
Gaurav Kumar
Patrick F Sullivan
Shaunna L Clark
Srilaxmi Nerella
P2860
P304
P356
10.1093/HMG/DDT511
P577
2013-10-16T00:00:00Z