Conjugates of oligonucleotides and modified oligonucleotides: a review of their synthesis and properties.
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Synthesis and antiviral activity of C-5 substituted analogues of d4T bearing methylamino- or methyldiamino-linker arms.Synthesis of modified nucleotide building blocks containing electrophilic groups in the 2'-position.Reversible photocycloaddition of a 4',5'-dihydropsoralen derivative with thymine.Making drugs out of oligonucleotides: a brief review and perspective.Fluorescent analogs of biomolecular building blocks: design, properties, and applications.Protein-DNA charge transport: redox activation of a DNA repair protein by guanine radical.Covalent cross-linking of duplex DNA using 4-thio-2'-deoxyuridine as a readily modifiable platform for introduction of reactive functionality into oligonucleotidesSequence specific inhibition of DNA restriction enzyme cleavage by PNA.Real time kinetics of restriction endonuclease cleavage monitored by fluorescence resonance energy transfer.A versatile solid support system for oligodeoxynucleotide probe-based hybridization assays.Association of antisense oligonucleotides with lipoproteins prolongs the plasma half-life and modifies the tissue distribution.The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transferDNA-multichromophore systemsModification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacyAntisense oligonucleotides as therapeutics for hyperlipidaemias.Cellular uptake and biological effects of antisense oligodeoxynucleotide analogs targeted to herpes simplex virus.Spatially-interactive biomolecular networks organized by nucleic acid nanostructures.Charge equilibration between two distinct sites in double helical DNA.3'-modified antisense oligodeoxyribonucleotides complementary to calmodulin mRNA alter behavioral responses in Paramecium.Intracellular distribution of microinjected antisense oligonucleotides.Oligonucleotide-mediated triple helix formation using an N3-protonated deoxycytidine analog exhibiting pH-independent binding within the physiological range.Nucleic acid-guided assembly of aromatic chromophores.Radiolabeled oligonucleotides for antisense imaging.Nucleic acid amphiphiles: synthesis and self-assembled nanostructures.Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy.Prospects for the therapeutic use of antigene oligonucleotides.A high-capacity column for affinity purification of sequence-specific DNA-binding proteins.Hybridization properties of deoxyoligonucleotides containing anthraquinone pseudonucleosides.Triplex-forming oligonucleotides trigger conformation changes of a target hairpin sequence.Polyamine-oligonucleotide conjugates: a promising direction for nucleic acid tools and therapeutics.Oligodeoxynucleoside phosphoramidates (P-NH2): synthesis and thermal stability of duplexes with DNA and RNA targetsSite specific labelling of sugar residues in oligoribonucleotides: reactions of aliphatic isocyanates with 2' amino groups.The acridine ring selectively intercalated into a DNA helix at various types of abasic sites: double strand formation and photophysical properties.Site-specific and photo-induced alkylation of DNA by a dimethylanthraquinone-oligodeoxynucleotide conjugate.Solid phase-supported thymine dimers for the construction of dimer-containing DNA by combined chemical and enzymatic synthesis: a potentially general method for the efficient incorporation of modified nucleotides into DNA.Structural properties of DNA:RNA duplexes containing 2'-O-methyl and 2'-S-methyl substitutions: a molecular dynamics investigation.Antisense 2'-O-alkyl oligoribonucleotides are efficient inhibitors of reverse transcription.Catalytic site-specific cleavage of a DNA-target by an oligonucleotide carrying bleomycin A5.Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity.Hybridization-based affinity partitioning of nucleic acids using PEG-coupled oligonucleotides.
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P2860
Conjugates of oligonucleotides and modified oligonucleotides: a review of their synthesis and properties.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Conjugates of oligonucleotides ...... heir synthesis and properties.
@en
Conjugates of oligonucleotides ...... heir synthesis and properties.
@nl
type
label
Conjugates of oligonucleotides ...... heir synthesis and properties.
@en
Conjugates of oligonucleotides ...... heir synthesis and properties.
@nl
prefLabel
Conjugates of oligonucleotides ...... heir synthesis and properties.
@en
Conjugates of oligonucleotides ...... heir synthesis and properties.
@nl
P356
P1476
Conjugates of oligonucleotides ...... heir synthesis and properties.
@en
P2093
Goodchild J
P304
P356
10.1021/BC00003A001
P577
1990-05-01T00:00:00Z