Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses.
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Robust tumor immunity to melanoma mediated by interleukin-9-producing T cellsRoutes of delivery for CpG and anti-CD137 for the treatment of orthotopic kidney tumors in miceThe development and in vivo function of T helper 9 cellsTherapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies.The role of interleukin-9 in lymphoma.Inhibition of adaptive immunity by IL9 can be disrupted to achieve rapid T-cell sensitization and rejection of progressive tumor challenges.Combined stimulation of IL-2 and 4-1BB receptors augments the antitumor activity of E7 DNA vaccines by increasing Ag-specific CTL responses.Association between low expression levels of interleukin-9 and colon cancer progression.4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression.Th9 cells promote antitumor immune responses in vivoA deleterious role for Th9/IL-9 in hepatic fibrogenesis.Context and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditionsNotch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells.Interleukin-9 Promotes Pancreatic Cancer Cells Proliferation and Migration via the miR-200a/Beta-Catenin Axis.Interleukin-12: clinical usage and molecular markers of cancer susceptibility.Immune classification of colorectal cancer patients: impressive but how complete?OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal.TNF superfamily cytokines in the promotion of Th9 differentiation and immunopathology.Amazing IL-9: revealing a new function for an "old" cytokineConstitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production.Immune profiling of melanoma tumors reflecting aggressiveness in a preclinical model.
P2860
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P2860
Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 July 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Signals through 4-1BB inhibit ...... enhancing antitumor responses.
@en
Signals through 4-1BB inhibit ...... enhancing antitumor responses.
@nl
type
label
Signals through 4-1BB inhibit ...... enhancing antitumor responses.
@en
Signals through 4-1BB inhibit ...... enhancing antitumor responses.
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prefLabel
Signals through 4-1BB inhibit ...... enhancing antitumor responses.
@en
Signals through 4-1BB inhibit ...... enhancing antitumor responses.
@nl
P2093
P2860
P1476
Signals through 4-1BB inhibit ...... enhancing antitumor responses
@en
P2093
Ana Lucia Dominguez
Jacques Van Snick
Joseph Lustgarten
Shannon E Smith
P2860
P2888
P304
P356
10.1007/S00262-011-1075-6
P577
2011-07-26T00:00:00Z