Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep.
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Increased adrenergic signaling is responsible for decreased glucose-stimulated insulin secretion in the chronically hyperinsulinemic ovine fetusFetal adrenal demedullation lowers circulating norepinephrine and attenuates growth restriction but not reduction of endocrine cell mass in an ovine model of intrauterine growth restrictionPlacental insufficiency decreases pancreatic vascularity and disrupts hepatocyte growth factor signaling in the pancreatic islet endothelial cell in fetal sheepFunction and expression of sulfonylurea, adrenergic, and glucagon-like peptide 1 receptors in isolated porcine islets.Adrenal Demedullation and Oxygen Supplementation Independently Increase Glucose-Stimulated Insulin Concentrations in Fetal Sheep With Intrauterine Growth RestrictionChallenges in nourishing the intrauterine growth-restricted foetus - Lessons learned from studies in the intrauterine growth-restricted foetal sheep.RNA Sequencing Exposes Adaptive and Immune Responses to Intrauterine Growth Restriction in Fetal Sheep Islets.Islet adaptations in fetal sheep persist following chronic exposure to high norepinephrine.Fetal adaptations in insulin secretion result from high catecholamines during placental insufficiency.Chronic anemic hypoxemia attenuates glucose-stimulated insulin secretion in fetal sheep.The impact of IUGR on pancreatic islet development and β-cell function.Enhanced insulin secretion and insulin sensitivity in young lambs with placental insufficiency-induced intrauterine growth restriction.Acute exposure of primary rat soleus muscle to zilpaterol HCl (β2 adrenergic agonist), TNFα, or IL-6 in culture increases glucose oxidation rates independent of the impact on insulin signaling or glucose uptake.A 1 week IGF-1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep
P2860
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P2860
Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep.
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2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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name
Enhanced insulin secretion res ...... s discontinued in fetal sheep.
@en
Enhanced insulin secretion res ...... s discontinued in fetal sheep.
@nl
type
label
Enhanced insulin secretion res ...... s discontinued in fetal sheep.
@en
Enhanced insulin secretion res ...... s discontinued in fetal sheep.
@nl
prefLabel
Enhanced insulin secretion res ...... s discontinued in fetal sheep.
@en
Enhanced insulin secretion res ...... s discontinued in fetal sheep.
@nl
P2093
P2860
P1476
Enhanced insulin secretion res ...... is discontinued in fetal sheep
@en
P2093
Alice S Green
Amy C Kelly
Antoni R Macko
Sean W Limesand
P2860
P304
P356
10.1152/AJPENDO.00517.2013
P577
2013-11-19T00:00:00Z