Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy
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Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computingAnakinra as an interleukin 1 receptor antagonist, complicated genetics and molecular impacts--from the point of view of mouse genomics.Interleukin-1 deficiency prolongs ovarian lifespan in mice.Interleukin-1 and acute brain injury.Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice.Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?The double-stranded RNA analogue polyinosinic-polycytidylic acid induces keratinocyte pyroptosis and release of IL-36γ.Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation.Autoinflammatory Skin Disorders: The Inflammasomme in Focus.Cytokine-receptor interactions as drug targets.Understanding the role of inflammatory-related pathways in the pathophysiology and treatment of psychiatric disorders: evidence from human peripheral studies and CNS studies.Targeting the IL-1 family members in skin inflammation.Targeting neuroinflammation for therapeutic intervention in neurodegenerative pathologies: a role for the peptide analogue of thymulin (PAT).The role of markers of inflammation in traumatic brain injury.The role of inflammation and interleukin-1 in acute cerebrovascular disease.Neuroinflammation after intracerebral hemorrhage.Interleukin-1α and brain inflammation.Concerted Action of PGC-1-related Coactivator (PRC) and c-MYC in the Stress Response to Mitochondrial Dysfunction.Mesenchymal stem cells as a double-edged sword in suppression or progression of solid tumor cells.Relationship Between Obesity, Alzheimer's Disease, and Parkinson's Disease: an Astrocentric View.Acidosis drives damage-associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathway.Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation.Immunomodulatory efficiency of poly(2-oxazolines).Urban air pollution targets the dorsal vagal complex and dark chocolate offers neuroprotection.Release of interleukin-1α or interleukin-1β depends on mechanism of cell death.NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury.Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system.The full-length interleukin-33 (FLIL33)-importin-5 interaction does not regulate nuclear localization of FLIL33 but controls its intracellular degradation.Redefining the ancestral origins of the interleukin-1 superfamily.
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Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Dual functionality of interleu ...... for anti-interleukin-1 therapy
@en
Dual functionality of interleu ...... or anti-interleukin-1 therapy.
@nl
type
label
Dual functionality of interleu ...... for anti-interleukin-1 therapy
@en
Dual functionality of interleu ...... or anti-interleukin-1 therapy.
@nl
prefLabel
Dual functionality of interleu ...... for anti-interleukin-1 therapy
@en
Dual functionality of interleu ...... or anti-interleukin-1 therapy.
@nl
P2860
P1476
Dual functionality of interleu ...... for anti-interleukin-1 therapy
@en
P2093
N J Rothwell
N M Luheshi
P2860
P304
P356
10.1111/J.1476-5381.2009.00331.X
P407
P50
P577
2009-08-01T00:00:00Z