Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
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Heterogeneous nuclear ribonucleoprotein K modulates angiotensinogen gene expression in kidney cellsThe paired homeodomain transcription factor Pax-2 is expressed in the endocrine pancreas and transactivates the glucagon gene promoter.Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element.Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.FoxO1 is required for the regulation of preproglucagon gene expression by insulin in pancreatic alphaTC1-9 cells.The role of incretins in glucose homeostasis and diabetes treatment.The role of the Wnt signaling pathway in incretin hormone production and function.Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes.Glucagon gene expression is negatively regulated by hepatocyte nuclear factor 3 beta.Elements responsible for hormonal control and tissue specificity of L-type pyruvate kinase gene expression in transgenic mice.The caudal-related homeodomain protein Cdx-2/3 regulates glucagon gene expression in islet cells.Pax6 regulates the proglucagon processing enzyme PC2 and its chaperone 7B2.Insulin as a physiological modulator of glucagon secretion.The metabolic actions of glucagon revisitedp21-Activated protein kinases and their emerging roles in glucose homeostasis.Islet-specific proteins interact with the insulin-response element of the glucagon gene.Insulin responsiveness of the glucagon gene conferred by interactions between proximal promoter and more distal enhancer-like elements involving the paired-domain transcription factor Pax6.A sequence element in the GLUT4 gene that mediates repression by insulin.Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1.Examination of a plasmid-based reverse genetics system for human astrovirus.The New Biology and Pharmacology of Glucagon.The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis.Negative regulation of adiponectin receptor 1 promoter by insulin via a repressive nuclear inhibitory protein element.Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression.Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP.Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences.Role of insulin-like growth factor-I in regulating estrogen receptor-alpha gene expression.A consensus insulin response element is activated by an Ets-related transcription factor.Somatostatin coordinately regulates glucagon gene expression and exocytosis in HIT-T15 cellsTranscriptional control of genes that regulate glycolysis and gluconeogenesis in adult liver.The three insulin response sequences in the glucose-6-phosphatase catalytic subunit gene promoter are functionally distinct.Functional characterization of somatostatin receptors expressed on hamster glucagonoma cells.CTCF mediates effect of insulin on glucagon expression.Effects of glucose and insulin on rat apolipoprotein A-I gene expression.Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development.
P2860
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P2860
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
@en
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
@nl
type
label
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
@en
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
@nl
prefLabel
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
@en
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
@nl
P2860
P356
P1476
Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element.
@en
P2093
Philippe J
P2860
P304
P356
10.1073/PNAS.88.16.7224
P407
P577
1991-08-01T00:00:00Z