Targeted approaches for gene therapy and the emergence of engineered meganucleases.
about
Targeting DNA double-strand breaks with TAL effector nucleasesGeneration of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffoldsIn Vivo Delivery Systems for Therapeutic Genome EditingMolecular basis of engineered meganuclease targeting of the endogenous human RAG1 locusEvolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site SpecificitySuccessful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI.Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells.TALE-PvuII fusion proteins--novel tools for gene targeting.Efficient gene targeting mediated by a lentiviral vector-associated meganucleasePhysiological and tissue-specific vectors for treatment of inherited diseases.Disease correction the iPSC way: advances in iPSC-based therapy.Artificial DNA cutters for DNA manipulation and genome engineering.Towards artificial metallonucleases for gene therapy: recent advances and new perspectives.Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases.Targeting herpetic keratitis by gene therapy.Gene transfer of integration defective anti-HSV-1 meganuclease to human corneas ex vivo.Context dependence between subdomains in the DNA binding interface of the I-CreI homing endonuclease.Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool.Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI.Effect of DNA on the conformational dynamics of the endonucleases I-DmoI as provided by molecular dynamics simulations.
P2860
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P2860
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
@en
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
@nl
type
label
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
@en
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
@nl
prefLabel
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
@en
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
@nl
P2093
P2860
P1476
Targeted approaches for gene therapy and the emergence of engineered meganucleases.
@en
P2093
Frédéric Pâques
Philippe Duchateau
Roman Galetto
P2860
P304
P356
10.1517/14712590903213669
P407
P577
2009-10-01T00:00:00Z