The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice
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Maternal Weaning Modulates Emotional Behavior and Regulates the Gut-Brain Axis.Romantic Love vs. Drug Addiction May Inspire a New Treatment for AddictionA Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice.The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition.Parvalbumin Interneurons of Central Amygdala Regulate the Negative Affective States and the Expression of Corticotrophin-Releasing Hormone During Morphine Withdrawal.A two-week pilot study of intranasal oxytocin for cocaine-dependent individuals receiving methadone maintenance treatment for opioid use disorderRegion specific up-regulation of oxytocin receptors in the opioid oprm1 (-/-) mouse model of autism.Oxytocin prevents ethanol actions at δ subunit-containing GABAA receptors and attenuates ethanol-induced motor impairment in ratsTargeting the Oxytocin System to Treat Addictive Disorders: Rationale and Progress to DateEmotional Impairment and Persistent Upregulation of mGlu5 Receptor following Morphine Abstinence: Implications of an mGlu5-MOPr Interaction.Carbetocin is a Functional Selective Gq Agonist That Does Not Promote Oxytocin Receptor Recycling After Inducing β-Arrestin-Independent InternalisationTherapies in early development for the treatment of opiate addiction.Severity of Withdrawal Symptoms, Plasma Oxytocin Levels, and Treatment Outcome in Heroin Users Undergoing Acute Withdrawal.μ opioid receptor, social behaviour and autism spectrum disorder: reward matters.Oxytocin for the treatment of drug and alcohol use disorders.Oxytocin and opioid addiction revisited: old drug, new applications.Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol.A critical role of striatal A2A R-mGlu5 R interactions in modulating the psychomotor and drug-seeking effects of methamphetamine.Chronic Intranasal Oxytocin has Dose-dependent Effects on Central Oxytocin and Vasopressin Systems in Prairie Voles (Microtus ochrogaster).Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans.Oxytocin Reduces Cocaine Cued Fos Activation in a Regionally Specific Manner.The Multidimensional Therapeutic Potential of Targeting the Brain Oxytocin System for the Treatment of Substance Use Disorders.Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains.Differential regulation of mGlu5 R and ΜOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice.CRF2 receptor-deficiency eliminates social behaviour deficits and vulnerability induced by cocaine.Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding.Adolescent pre-treatment with oxytocin protects against adult methamphetamine-seeking behavior in female rats.Impairment of opiate-mediated behaviors by the selective TRPV1 antagonist SB366791.Anti-stress neuropharmacological mechanisms and targets for addiction treatment: A translational framework
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The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The oxytocin analogue carbetoc ...... ing in morphine-abstinent mice
@en
The oxytocin analogue carbetoc ...... ng in morphine-abstinent mice.
@nl
type
label
The oxytocin analogue carbetoc ...... ing in morphine-abstinent mice
@en
The oxytocin analogue carbetoc ...... ng in morphine-abstinent mice.
@nl
prefLabel
The oxytocin analogue carbetoc ...... ing in morphine-abstinent mice
@en
The oxytocin analogue carbetoc ...... ng in morphine-abstinent mice.
@nl
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P1476
The oxytocin analogue carbetoc ...... ing in morphine-abstinent mice
@en
P2093
Ian Kitchen
Panos Zanos
Polymnia Georgiou
Raphaëlle Winsky-Sommerer
Sherie R Wright
Susanna M Hourani
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P2888
P304
P356
10.1038/NPP.2013.285
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P577
2013-10-15T00:00:00Z