Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes.
about
UHRF1 is required for basal stem cell proliferation in response to airway injury.Methylation maintains HSC division fate.PIM1 induces cellular senescence through phosphorylation of UHRF1 at Ser311.Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression.Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection.FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.Med23 serves as a gatekeeper of the myeloid potential of hematopoietic stem cells
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Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes.
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 12 December 2016
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Uhrf1 controls the self-renewa ...... ating the cell-division modes.
@en
Uhrf1 controls the self-renewa ...... ating the cell-division modes.
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type
label
Uhrf1 controls the self-renewa ...... ating the cell-division modes.
@en
Uhrf1 controls the self-renewa ...... ating the cell-division modes.
@nl
prefLabel
Uhrf1 controls the self-renewa ...... ating the cell-division modes.
@en
Uhrf1 controls the self-renewa ...... ating the cell-division modes.
@nl
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P2860
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Uhrf1 controls the self-renewa ...... ating the cell-division modes.
@en
P2093
Guangrong Song
Haifeng Liu
Jiali Zhang
Jingyao Zhao
Xiaolong Liu
Xufeng Chen
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P304
P356
10.1073/PNAS.1612967114
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P577
2016-12-12T00:00:00Z