Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction
about
Design of versatile biochemical switches that respond to amplitude, duration, and spatial cuesThe signaling petri net-based simulator: a non-parametric strategy for characterizing the dynamics of cell-specific signaling networksNetwork analysis of oncogenic Ras activation in cancer.A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation.Computational model explains high activity and rapid cycling of Rho GTPases within protein complexesBoth ligand- and cell-specific parameters control ligand agonism in a kinetic model of g protein-coupled receptor signaling.Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAPKinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cellsCell-signalling dynamics in time and space.A kinetic model for calcium dynamics in RAW 264.7 cells: 1. Mechanisms, parameters, and subpopulational variability.A kinetic model for calcium dynamics in RAW 264.7 cells: 2. Knockdown response and long-term response.Reduced-order modelling of biochemical networks: application to the GTPase-cycle signalling moduleSystems biology analysis of G protein and MAP kinase signaling in yeast.Modeling of G-protein-coupled receptor signaling pathways.Mixed-integer nonlinear optimisation approach to coarse-graining biochemical networks.Diffusion-limited reactions in G-protein activation: unexpected consequences of antagonist and agonist competition.G proteins in reverse mode: receptor-mediated GTP release inhibits G protein and effector function.Collision coupling, crosstalk, and compartmentalization in G-protein coupled receptor systems: can a single model explain disparate results?Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.RGS proteins maintain robustness of GPCR-GIRK coupling by selective stimulation of the G protein subunit Gαo.Mathematical model of PAR1-mediated activation of human platelets.
P2860
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P2860
Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-sg
2004年學術文章
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name
Computational modeling reveals ...... regulates signal transduction
@en
Computational modeling reveals ...... regulates signal transduction.
@nl
type
label
Computational modeling reveals ...... regulates signal transduction
@en
Computational modeling reveals ...... regulates signal transduction.
@nl
prefLabel
Computational modeling reveals ...... regulates signal transduction
@en
Computational modeling reveals ...... regulates signal transduction.
@nl
P2093
P2860
P356
P1476
Computational modeling reveals ...... regulates signal transduction
@en
P2093
Mano R Maurya
Marilyn Gist Farquhar
Scott J Bornheimer
Shankar Subramaniam
P2860
P304
15899-15904
P356
10.1073/PNAS.0407009101
P407
P577
2004-11-01T00:00:00Z