The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor.
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Discovery of the first insect nidovirus, a missing evolutionary link in the emergence of the largest RNA virus genomesFunctional and genetic analysis of coronavirus replicase-transcriptase proteinsA second, non-canonical RNA-dependent RNA polymerase in SARS CoronavirusLocalization and Membrane Topology of Coronavirus Nonstructural Protein 4: Involvement of the Early Secretory Pathway in ReplicationTopology and Membrane Anchoring of the Coronavirus Replication Complex: Not All Hydrophobic Domains of nsp3 and nsp6 Are Membrane SpanningDynamics of coronavirus replication-transcription complexes.Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric SwitchStructural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15Structure of the C-terminal domain of nsp4 from feline coronavirusBiochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein ComplexGenome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replicationSite-directed mutagenesis of the Nidovirus replicative endoribonuclease NendoU exerts pleiotropic effects on the arterivirus life cycle.Characterization of a torovirus main proteinaseSARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitroInfidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing.An insect nidovirus emerging from a primary tropical rainforestSARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavageAlphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysateDiscovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesisUltrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complexNew antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15.Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradationCoronaviruses: an RNA proofreading machine regulates replication fidelity and diversity.Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression.The structure and functions of coronavirus genomic 3' and 5' ends.Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication.Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus Suppresses Both MAVS and RIG-I Expression as One of the Mechanisms to Antagonize Type I Interferon Production.Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replicationRNA binding by the NS3 protease of the hepatitis C virusHigh fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.Crystallization and preliminary X-ray diffraction analysis of Nsp15 from SARS coronavirus.Comparative in vivo analysis of the nsp15 endoribonuclease of murine, porcine and severe acute respiratory syndrome coronaviruses.A contemporary view of coronavirus transcription.A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of Porcine Reproductive and Respiratory Syndrome Virus nsp11.SARS coronavirus replicase proteins in pathogenesis.Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease.Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signalingEndoU is a novel regulator of AICD during peripheral B cell selection.In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins.
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The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-my
2004年学术文章
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name
The severe acute respiratory s ...... efers manganese as a cofactor.
@en
The severe acute respiratory s ...... efers manganese as a cofactor.
@nl
type
label
The severe acute respiratory s ...... efers manganese as a cofactor.
@en
The severe acute respiratory s ...... efers manganese as a cofactor.
@nl
prefLabel
The severe acute respiratory s ...... efers manganese as a cofactor.
@en
The severe acute respiratory s ...... efers manganese as a cofactor.
@nl
P2093
P2860
P1433
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The severe acute respiratory s ...... efers manganese as a cofactor.
@en
P2093
C Cheng Kao
Kanchan Bhardwaj
Linda Guarino
P2860
P304
12218-12224
P356
10.1128/JVI.78.22.12218-12224.2004
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P577
2004-11-01T00:00:00Z