Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map. - Wikidata - wikimedia - TriplyDB

Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.

Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.

http://www.wikidata.org/entity/Q37597058

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Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement Human β-cell proliferation and intracellular signaling: part 3 Regenerative medicine in diabetes Natural history of β-cell adaptation and failure in type 2 diabetes SerpinB1 Promotes Pancreatic β Cell Proliferation Neuropeptide Y expression marks partially differentiated β cells in mice and humans Increasing β-cell mass requires additional stimulation for adaptation to secretory demand Recent progress in studies of factors that elicit pancreatic β-cell expansion The window period of NEUROGENIN3 during human gestation.Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets.Anti-incretin, Anti-proliferative Action of Dopamine on β-Cells Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease.Betatrophin in Diabetes Mellitus: the Epidemiological Evidence in Humans.Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic β- and α-Cells.Direct effect of glucocorticoids on glucose-activated adult rat β-cells increases their cell number and their functional mass for transplantation.Insulin demand regulates β cell number via the unfolded protein response.Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion.The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice WS6 induces both alpha and beta cell proliferation without affecting differentiation or viability.Inhibition of DYRK1A Stimulates Human β-Cell Proliferation Replicative capacity of β-cells and type 1 diabetes.The Genetic Program of Pancreatic β-Cell Replication In Vivo Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass Mild hyperglycemia triggered islet function recovery in streptozotocin-induced insulin-deficient diabetic rats.The regulation of pre- and post-maturational plasticity of mammalian islet cell mass.Diabetes mellitus--advances and challenges in human β-cell proliferation.Role of transcription factors in the transdifferentiation of pancreatic islet cells.Current management of diabetes mellitus and future directions in care.Cell cycle-related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line.Inferring Intracellular Signal Transduction Circuitry from Molecular Perturbation Experiments.Histone chaperone ASF1B promotes human β-cell proliferation via recruitment of histone H3.3.Role of Sex Steroids in β Cell Function, Growth, and Survival.Synergistic activations of REG I α and REG I β promoters by IL-6 and Glucocorticoids through JAK/STAT pathway in human pancreatic β cells.Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass.Novel factors modulating human β-cell proliferation.Advances in β cell replacement and regeneration strategies for treating diabetes

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Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.

http://www.wikidata.org/entity/Q37597058

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on March 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Human β-cell proliferation and ...... n the dark without a road map.

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Human β-cell proliferation and ...... n the dark without a road map.

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Human β-cell proliferation and ...... n the dark without a road map.

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Human β-cell proliferation and ...... n the dark without a road map.

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Human β-cell proliferation and ...... n the dark without a road map.

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Human β-cell proliferation and ...... n the dark without a road map.

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Human β-cell proliferation and ...... n the dark without a road map.

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Adolfo Garcia-Ocaña

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Andrew F Stewart

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Donald K Scott

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Ernesto Bernal-Mizrachi

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Franck Mauvais-Jarvis

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Rohit N Kulkarni

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Creative Commons Attribution-NonCommercial-NoDerivatives

P2860

Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation

Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity

Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation

Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression

Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

Wnt/beta-catenin signaling is required for development of the exocrine pancreas

Beta-catenin is essential for pancreatic acinar but not islet development

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819-831

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scholarly article

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10.2337/DB13-1146

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3

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63

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2014-03-01T00:00:00Z

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260552689

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24556859

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endocrine system

Aizkuņģa dziedzeris

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3931400

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