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Autoimmune therapies targeting costimulation and emerging trends in multivalent therapeuticsModulation of GITR for cancer immunotherapyMolecular mechanisms of T cell co-stimulation and co-inhibitionHuman cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γExpansion of regulatory GITR+CD25 low/-CD4+ T cells in systemic lupus erythematosus patients.The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice.Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.Glucocorticoid-induced tumour necrosis factor receptor-related protein: a key marker of functional regulatory T cells.TNF superfamily in inflammatory disease: translating basic insights.Induction of GITRL expression in human keratinocytes by Th2 cytokines and TNF-α: implications for atopic dermatitis.Pharmacological modulation of GITRL/GITR system: therapeutic perspectives.Converging mediators from immune and trophic pathways to identify Parkinson disease dementia.Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells.NKT cell costimulation: experimental progress and therapeutic promiseCrystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway.Correlation of increased blood levels of GITR and GITRL with disease severity in patients with primary Sjögren's syndromeThe influence of antigen targeting to sub-cellular compartments on the anti-allergic potential of a DNA vaccine.T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy.Importance of reverse signaling of the TNF superfamily in immune regulation.The contextual role of TNFR family members in CD8(+) T-cell control of viral infections.Costimulatory pathways in kidney transplantation: pathogenetic role, clinical significance and new therapeutic opportunities.Enhancement of antibody-dependent cell mediated cytotoxicity: a new era in cancer treatment.Characterization of a new regulatory CD4+ T cell subset in primary Sjögren's syndrome.Generation and preclinical characterization of a Fc-optimized GITR-Ig fusion protein for induction of NK cell reactivity against leukemia.GITR-expressing regulatory T-cell subsets are increased in tumor-positive lymph nodes from advanced breast cancer patients as compared to tumor-negative lymph nodes.B Cell Requirement for Robust Regulatory T Cell Responses to Friend Retrovirus Infection.T-cell suppression mediated by regulatory T cells infiltrating hepatic tumors can be overcome by GITRL treatment.GITRL as a genetic adjuvant enhances enterovirus 71 VP1 DNA vaccine immunogenicity.Opposing roles for TRAF1 in the alternative versus classical NF-κB pathway in T cells.A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand.Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice.Sjögren's syndrome-like autoimmune sialadenitis in MRL-Faslpr mice is associated with expression of glucocorticoid-induced TNF receptor-related protein (GITR) ligand and 4-1BB ligand.Modulation of tumor immunity: a patent evaluation of WO2015026684A1.Overview of Basic Immunology for Clinical Investigators.Frequency and expression of inhibitory markers of CD4(+) CD25(+) FOXP3(+) regulatory T cells in patients with common variable immunodeficiency.GITRL is associated with increased autoantibody production in patients with rheumatoid arthritis.CD8+ T cells: GITR matters.Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
GITR: a modulator of immune response and inflammation.
@en
GITR: a modulator of immune response and inflammation.
@nl
type
label
GITR: a modulator of immune response and inflammation.
@en
GITR: a modulator of immune response and inflammation.
@nl
prefLabel
GITR: a modulator of immune response and inflammation.
@en
GITR: a modulator of immune response and inflammation.
@nl
P1476
GITR: a modulator of immune response and inflammation
@en
P2093
Carlo Riccardi
Giuseppe Nocentini
P304
P356
10.1007/978-0-387-89520-8_11
P407
P577
2009-01-01T00:00:00Z