Oxidative damage in MauG: implications for the control of high-valent iron species and radical propagation pathways.
about
Site-Directed Mutagenesis of Gln103 Reveals the Influence of This Residue on the Redox Properties and Stability of MauGProbing Bis-FeIV MauG: Isolation of Highly Reactive Radical Intermediates.Probing bis-Fe(IV) MauG: experimental evidence for the long-range charge-resonance model.A T67A mutation in the proximal pocket of the high-spin heme of MauG stabilizes formation of a mixed-valent FeII/FeIII state and enhances charge resonance stabilization of the bis-FeIV state.Roles of multiple-proton transfer pathways and proton-coupled electron transfer in the reactivity of the bis-FeIV state of MauG.Mechanism of protein oxidative damage that is coupled to long-range electron transfer to high-valent haems.Bis-Fe(IV): nature's sniper for long-range oxidation.LC-MS/MS suggests that hole hopping in cytochrome c peroxidase protects its heme from oxidative modification by excess H2O2.A Suicide Mutation Affecting Proton Transfers to High-Valent Hemes Causes Inactivation of MauG during Catalysis.Mutual synergy between catalase and peroxidase activities of the bifunctional enzyme KatG is facilitated by electron hole-hopping within the enzyme.Ascorbate protects the diheme enzyme, MauG, against self-inflicted oxidative damage by an unusual antioxidant mechanism.Properties of the high-spin heme of MauG are altered by binding of preMADH at the protein surface 40 Å away.Protein-Derived Cofactors Revisited: Empowering Amino Acid Residues with New Functions.
P2860
Q27681679-FB8D2EE6-0F7A-4053-8190-22EA719C26EDQ30101088-F02F1A30-FFB7-4413-97B1-955843F6BE04Q35188543-9CF8FBEB-44E8-4EFB-AFCD-AA621757DB29Q35690451-C68D3B4D-5504-4938-A4DE-BCEFC33A1526Q36055561-E5D830FE-310E-4383-ADEE-2155859D2788Q36995376-ECF13233-1237-4FCE-90C6-45AC567D1C8DQ38203816-5EAF7783-83EE-46B1-BE41-6BE12D61F98EQ41965338-338B90B4-E0DB-4F84-950D-C979318636D0Q41990838-9C96797B-0926-4F20-B674-D97743193146Q46296304-D5DC7E45-C5CB-4328-A812-4D57324962C7Q46347082-EA92247C-CDCA-4A4A-A6EB-53D624EDB163Q48170764-EE3C2602-C135-4D67-BD9F-45ED783CA502Q52677195-0E1F4106-A189-43ED-A226-FF24D72F3D77
P2860
Oxidative damage in MauG: implications for the control of high-valent iron species and radical propagation pathways.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Oxidative damage in MauG: impl ...... radical propagation pathways.
@en
Oxidative damage in MauG: impl ...... radical propagation pathways.
@en-gb
Oxidative damage in MauG: impl ...... radical propagation pathways.
@nl
type
label
Oxidative damage in MauG: impl ...... radical propagation pathways.
@en
Oxidative damage in MauG: impl ...... radical propagation pathways.
@en-gb
Oxidative damage in MauG: impl ...... radical propagation pathways.
@nl
prefLabel
Oxidative damage in MauG: impl ...... radical propagation pathways.
@en
Oxidative damage in MauG: impl ...... radical propagation pathways.
@en-gb
Oxidative damage in MauG: impl ...... radical propagation pathways.
@nl
P2860
P50
P356
P1433
P1476
Oxidative damage in MauG: impl ...... radical propagation pathways.
@en
P2093
LeeAnn Higgins
P2860
P304
P356
10.1021/BI401441H
P407
P577
2013-12-16T00:00:00Z