Role of microRNAs in the regulation of drug metabolism and disposition.
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Psychedelic 5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actionsmicroRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessmentThe effects of microRNA on the absorption, distribution, metabolism and excretion of drugsMiRNAs and miRNA Polymorphisms Modify Drug ResponseIdentification of Differentially Expressed microRNAs between the Fenpropathrin Resistant and Susceptible Strains in Tetranychus cinnabarinusGenetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance.microRNAs of parasitic helminths - Identification, characterization and potential as drug targets.Rapid production of novel pre-microRNA agent hsa-mir-27b in Escherichia coli using recombinant RNA technology for functional studies in mammalian cells.Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cellsmicroRNA-34a is associated with expression of key hepatic transcription factors and cytochromes P450MicroRNA expression is differentially altered by xenobiotic drugs in different human cell lines.Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional CharacterizationNon-coding RNAs--novel targets in neurotoxicity.Molecular targets related to inflammation and insulin resistance and potential interventionsCombination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth.MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyReducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.Small nucleolar RNA-derived microRNA hsa-miR-1291 modulates cellular drug disposition through direct targeting of ABC transporter ABCC1Potential role of epigenetic mechanisms in the regulation of drug metabolism and transport.The Promises of Quantitative Proteomics in Precision MedicineRole of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants.Importance of ABCC1 for cancer therapy and prognosis.MicroRNAs as key regulators of xenobiotic biotransformation and drug response.Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells.MicroRNA hsa-miR-29a-3p modulates CYP2C19 in human liver cells.Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice.Role of nanomedicine in reversing drug resistance mediated by ATP binding cassette transporters and P-glycoprotein in melanoma.microRNAs: a role in drug resistance in parasitic nematodes?Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells.Inverse association between microRNA-124a and ABCC4 in HepG2 cells treated with antiretroviral drugs.
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Role of microRNAs in the regulation of drug metabolism and disposition.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Role of microRNAs in the regulation of drug metabolism and disposition.
@en
Role of microRNAs in the regulation of drug metabolism and disposition.
@nl
type
label
Role of microRNAs in the regulation of drug metabolism and disposition.
@en
Role of microRNAs in the regulation of drug metabolism and disposition.
@nl
prefLabel
Role of microRNAs in the regulation of drug metabolism and disposition.
@en
Role of microRNAs in the regulation of drug metabolism and disposition.
@nl
P2860
P1476
Role of microRNAs in the regulation of drug metabolism and disposition.
@en
P2093
Ai-Ming Yu
P2860
P304
P356
10.1517/17425250903307448
P407
P577
2009-12-01T00:00:00Z