Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.

Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.

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http://www.wikidata.org/entity/Q37613222
In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cellsAn adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering.Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice.K Domain CR9 of Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1) Is Critical for Aggregated LDL-induced Foam Cell Formation from Human Vascular Smooth Muscle Cells.Statins inhibit blastocyst formation by preventing geranylgeranylation.Omentin attenuates atherosclerotic lesion formation in apolipoprotein E-deficient mice.Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism.AMPK activation enhances the anti-atherogenic effects of high density lipoproteins in apoE-/- mice.Inappropriate movement of Rac1 contributes to glucotoxicity of the islet β-cell.The complex interplay among hepatocytes and immune cells at the crossroad between inflammation and cholesterol metabolism in hyperglycemia.
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Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.

Item
http://www.wikidata.org/entity/Q37613222
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 January 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting GGTase-I activates R ...... duces atherosclerosis in mice.
@en
Targeting GGTase-I activates R ...... duces atherosclerosis in mice.
@nl
type
label
Targeting GGTase-I activates R ...... duces atherosclerosis in mice.
@en
Targeting GGTase-I activates R ...... duces atherosclerosis in mice.
@nl
prefLabel
Targeting GGTase-I activates R ...... duces atherosclerosis in mice.
@en
Targeting GGTase-I activates R ...... duces atherosclerosis in mice.
@nl
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Targeting GGTase-I activates R ...... duces atherosclerosis in mice.
@en
P2093
P2860
P304
P31
P356
10.1161/CIRCULATIONAHA.112.000588
P407
P433
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P50
P577
P698
P921
P932