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Targeting the Eph System with Peptides and Peptide ConjugatesStructural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based DesignThe cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: A proof-of-concept study using the integrin-binding RGD motifTotal chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6)Investigation of a MMP-2 activity-dependent anchoring probe for nuclear imaging of cancerNCAD, a database integrating the intrinsic conformational preferences of non-coded amino acids.Peptoid-Peptide hybrid ligands targeting the polo box domain of polo-like kinase 1.Conformational profile of a proline-arginine hybrid.Molecular inhibition of telomerase recruitment using designer peptides: an in silico approach.Novel preparation of chiral α-amino acids using the Mitsunobu-Tsunoda reaction.Spider-venom peptides as therapeutics.Cone snail venomics: from novel biology to novel therapeutics.A fascinating journey into history: exploration of the world of isonitriles en route to complex amidesA Protocol for the Design of Protein and Peptide Nanostructure Self-Assemblies Exploiting Synthetic Amino Acids.Endostatin's emerging roles in angiogenesis, lymphangiogenesis, disease, and clinical applications.New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic propertiesDevelopment of α-helical calpain probes by mimicking a natural protein-protein interaction.Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution."Click"-cyclized (68)Ga-labeled peptides for molecular imaging and therapy: synthesis and preliminary in vitro and in vivo evaluation in a melanoma model system.Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis.Antihypertensive peptides from food proteins: a review.New modalities in conformationally constrained peptides for potency, selectivity and cell permeation.New Modalities for Challenging Targets in Drug Discovery.Production of peptides as generic drugs: a patent landscape of octreotide.Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization.Enhanced serum proteolysis resistance of cell-penetrating peptides.Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action.Modifications of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor To Achieve High Plasma StabilityOn the synthesis of conformationally modified peptides through isonitrile chemistry: implications for dealing with polypeptide aggregationDevelopment of antibody arrays for monoclonal antibody Higher Order Structure analysis.Synthesis and SARs of indole-based α-amino acids as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.Nonnatural amino acid synthesis by using carbon-hydrogen bond functionalization methodologyRole of Disulfide Bonds in Activity and Stability of Tigerinin-1R.Discovery of Key Physicochemical, Structural, and Spatial Properties of RNA-Targeted Bioactive Ligands.Prediction and interpretation of the lipophilicity of small peptides.Metabolic stability of peptidomimetics: N-methyl and aza heptapeptide analogs of a PKB/Akt inhibitor.Stereoselective Synthesis of β-(5-Arylthiazolyl) α-Amino Acids and Use in Neurotensin AnaloguesInsights into the development of chemical probes for RNA
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The medicinal chemistry of peptides.
@en
The medicinal chemistry of peptides.
@nl
type
label
The medicinal chemistry of peptides.
@en
The medicinal chemistry of peptides.
@nl
prefLabel
The medicinal chemistry of peptides.
@en
The medicinal chemistry of peptides.
@nl
P1476
The medicinal chemistry of peptides.
@en
P2093
Nestor JJ Jr
P304
P356
10.2174/092986709789712907
P577
2009-01-01T00:00:00Z