Scientific and regulatory perspectives on metabolizing enzyme-transporter interplay and its role in drug interactions: challenges in predicting drug interactions.
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Evaluation of Adverse Drug Properties with Cryopreserved Human Hepatocytes and the Integrated Discrete Multiple Organ Co-culture (IdMOC(TM)) SystemThe effect of ketoconazole on the pharmacokinetics and pharmacodynamics of inhaled fluticasone furoate and vilanterol trifenatate in healthy subjects.Expression of drug transporters in human kidney: impact of sex, age, and ethnicity.Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in MiceStructure elucidation and biological activity of antibacterial compound from Micromonospora auratinigra, a soil Actinomycetes.Predicting drug-drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge.Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimal and noninvasive probes for hepatic and first-pass CYP3A induction.Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.Has the era of individualised medicine arrived for antifungals? A review of antifungal pharmacogenomics.The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance.Role of transporters in drug interactions.Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux.Biomarkers and human hepatocytes.Interplay of drug metabolizing enzymes with cellular transporters.Drug metabolism and drug interactions: potential application to antituberculosis drugs.Assessment of Amino Acid/Drug Transporters for Renal Transport of [18F]Fluciclovine (anti-[18F]FACBC) in Vitro.Transporters as Drug Targets in Neurological DiseasesFluticasone furoate and vilanterol trifenatate combination therapy for the treatment of asthma.Proteoliposomes as tool for assaying membrane transporter functions and interactions with xenobiotics.Solute Carrier (SLC) Family Transporters
P2860
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P2860
Scientific and regulatory perspectives on metabolizing enzyme-transporter interplay and its role in drug interactions: challenges in predicting drug interactions.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Scientific and regulatory pers ...... predicting drug interactions.
@en
Scientific and regulatory pers ...... predicting drug interactions.
@nl
type
label
Scientific and regulatory pers ...... predicting drug interactions.
@en
Scientific and regulatory pers ...... predicting drug interactions.
@nl
prefLabel
Scientific and regulatory pers ...... predicting drug interactions.
@en
Scientific and regulatory pers ...... predicting drug interactions.
@nl
P2093
P356
P1476
Scientific and regulatory pers ...... predicting drug interactions.
@en
P2093
Shiew-Mei Huang
Yuanchao Zhang
P304
P356
10.1021/MP900132E
P407
P577
2009-11-01T00:00:00Z