Trans splicing in trypanosomes requires methylation of the 5' end of the spliced leader RNA.
about
The spliced leader-associated RNA is a trypanosome-specific sn(o) RNA that has the potential to guide pseudouridine formation on the SL RNA.Enzymology of RNA cap synthesis3' processing in protistsFunctional characterization of a 48 kDa Trypanosoma brucei cap 2 RNA methyltransferaseCyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific ProteinA novel class of developmentally regulated noncoding RNAs in Leishmania.Novel and essential subunits in the 300-kilodalton nuclear cap binding complex of Trypanosoma brucei.Trypanosome capping enzymes display a novel two-domain structureExonic sequences in the 5' untranslated region of alpha-tubulin mRNA modulate trans splicing in Trypanosoma brucei.Transcription termination and 3'-End processing of the spliced leader RNA in kinetoplastidsCharacterization of a Trypanosoma brucei RNA cap (guanine N-7) methyltransferaseDouble-stranded RNA induces mRNA degradation in Trypanosoma brucei.Unconventional rules of small nuclear RNA transcription and cap modification in trypanosomatids.In vivo structural analysis of spliced leader RNAs in Trypanosoma brucei and Leptomonas collosoma: a flexible structure that is independent of cap4 methylations.Complete cap 4 formation is not required for viability in Trypanosoma brucei.Exportin 1 mediates nuclear export of the kinetoplastid spliced leader RNA.Roles of a Trypanosoma brucei 5'->3' exoribonuclease homolog in mRNA degradation.The spliceosomal PRP19 complex of trypanosomesThe 2'-O-ribose methyltransferase for cap 1 of spliced leader RNA and U1 small nuclear RNA in Trypanosoma brucei.Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts.Trypanosoma brucei spliced-leader RNA methylations are required for trans splicing in vivo.A trans-spliced telomerase RNA dictates telomere synthesis in Trypanosoma bruceiTrypanosome cdc2-related kinase 9 controls spliced leader RNA cap4 methylation and phosphorylation of RNA polymerase II subunit RPB1The roles of 3'-exoribonucleases and the exosome in trypanosome mRNA degradation.Trypanosoma brucei spliced leader RNA maturation by the cap 1 2'-O-ribose methyltransferase and SLA1 H/ACA snoRNA pseudouridine synthase complex.Evidence for a capping enzyme with specificity for the trypanosome spliced leader RNA.The role of deadenylation in the degradation of unstable mRNAs in trypanosomes.A conserved upstream element is essential for transcription of the Leishmania tarentolae mini-exon gene.Functional analysis of cis-acting DNA elements required for expression of the SL RNA gene in the parasitic protozoan Leishmania amazonensis.Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169Spliced leader RNA of trypanosomes: in vivo mutational analysis reveals extensive and distinct requirements for trans splicing and cap4 formation.A protein related to the vaccinia virus cap-specific methyltransferase VP39 is involved in cap 4 modification in Trypanosoma bruceisnRNA-specific role of SMN in trypanosome snRNP biogenesis in vivo.Inhibition of mRNA maturation in trypanosomes causes the formation of novel foci at the nuclear periphery containing cytoplasmic regulators of mRNA fate.Structure-function analysis of Trypanosoma brucei RNA triphosphatase and evidence for a two-metal mechanism.Macrocyclic amines as catalysts of the hydrolysis of the triphosphate bridge of the mRNA 5'-cap structure.Hydrolytic reactions of diadenosine 5',5'-triphosphate.Efficient trans-splicing of mutated spliced leader exons in Leishmania tarentolae.The Role of Cytoplasmic mRNA Cap-Binding Protein Complexes in Trypanosoma brucei and Other Trypanosomatids.The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity.
P2860
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P2860
Trans splicing in trypanosomes requires methylation of the 5' end of the spliced leader RNA.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Trans splicing in trypanosomes ...... end of the spliced leader RNA.
@en
Trans splicing in trypanosomes ...... end of the spliced leader RNA.
@nl
type
label
Trans splicing in trypanosomes ...... end of the spliced leader RNA.
@en
Trans splicing in trypanosomes ...... end of the spliced leader RNA.
@nl
prefLabel
Trans splicing in trypanosomes ...... end of the spliced leader RNA.
@en
Trans splicing in trypanosomes ...... end of the spliced leader RNA.
@nl
P2860
P356
P1476
Trans splicing in trypanosomes ...... end of the spliced leader RNA.
@en
P2093
P2860
P304
10074-10078
P356
10.1073/PNAS.88.22.10074
P407
P577
1991-11-01T00:00:00Z