Lessons from development: A role for asymmetric stem cell division in cancer. - Wikidata - wikimedia - TriplyDB

Lessons from development: A role for asymmetric stem cell division in cancer.

Lessons from development: A role for asymmetric stem cell division in cancer.

http://www.wikidata.org/entity/Q37620724

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Lessons from development: A role for asymmetric stem cell division in cancer.

http://www.wikidata.org/entity/Q37620724

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 25 September 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Lessons from development: A role for asymmetric stem cell division in cancer.

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Lessons from development: A role for asymmetric stem cell division in cancer.

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type

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Lessons from development: A role for asymmetric stem cell division in cancer.

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Lessons from development: A role for asymmetric stem cell division in cancer.

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Lessons from development: A role for asymmetric stem cell division in cancer.

@en

Lessons from development: A role for asymmetric stem cell division in cancer.

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J.SCR.2009.09.005

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Stem Cell Research

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Lessons from development: A role for asymmetric stem cell division in cancer.

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Anne E Powell

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Chia-Yi Shung

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Joseph B Weiss

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Karin A Müllendorff

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Katherine W Saylor

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Melissa H Wong

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P2860

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase

TRIM32 is an E3 ubiquitin ligase for dysbindin

The adenomatous polyposis coli protein (APC) exists in two distinct soluble complexes with different functions

Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division

Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

Asymmetric and symmetric stem-cell divisions in development and cancer

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scholarly article

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10.1016/J.SCR.2009.09.005

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