THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
about
Advances of small molecule targeting of kinases.Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling.ER stress signaling promotes the survival of cancer 'persister cells' tolerant to EGFR tyrosine kinase inhibitors.Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression.Chromatin dependencies in cancer and inflammation.Enhancer dysfunction in leukemia.The essential and multi-functional TFIIH complex.Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma.
P2860
Q39450797-CEF63D7B-87E8-4BCC-8FA3-523BC226F758Q40095304-1E6CB7C2-3630-4204-BAC8-70F4CB323FDCQ47273602-F35C7C21-D56E-4ECC-B337-BC62DDC133BCQ47671139-C695C76B-3DA6-4C38-90B1-D04459A6E22FQ49565575-01E996B8-B222-4A62-8C2D-06181D1B7DBCQ50028355-B716CCA3-FF44-4964-85F7-02C985EECEDFQ52319133-7CC2E10F-4AD8-494C-887C-7A743E21914CQ55177532-6A88481A-7ED6-457E-AEE9-E7ED0051DC7D
P2860
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 January 2017
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
THZ1 targeting CDK7 suppresses ...... l lymphomas to BCL2 inhibitors
@en
THZ1 targeting CDK7 suppresses ...... lymphomas to BCL2 inhibitors.
@nl
type
label
THZ1 targeting CDK7 suppresses ...... l lymphomas to BCL2 inhibitors
@en
THZ1 targeting CDK7 suppresses ...... lymphomas to BCL2 inhibitors.
@nl
prefLabel
THZ1 targeting CDK7 suppresses ...... l lymphomas to BCL2 inhibitors
@en
THZ1 targeting CDK7 suppresses ...... lymphomas to BCL2 inhibitors.
@nl
P2093
P2860
P50
P356
P1476
THZ1 targeting CDK7 suppresses ...... l lymphomas to BCL2 inhibitors
@en
P2093
Benet Pera
Florencia Cayrol
Giorgio Inghirami
Jude Phillip
Kaipol Takpradit
Lidia Roman
M Nieves Calvo-Vidal
Marcello Gaudiano
Nathanael S Gray
P2860
P2888
P356
10.1038/NCOMMS14290
P407
P577
2017-01-30T00:00:00Z