Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.
about
Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramideSphingosine-induced apoptosis is dependent on lysosomal proteasesInhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells.Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells.Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesisTumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids.Death receptor signals to mitochondria.Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia.Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation.Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cellsPhosphatidylcholine-specific phospholipase C regulates glutamate-induced nerve cell death.Fas-induced apoptosis of T cells occurs independently of ceramide generationCeramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases.Integration of cytokine biology and lipid metabolism in strokeCeramide function in the brain: when a slight tilt is enough.Phospholipase A2 functions in Pseudomonas aeruginosa-induced apoptosisActivation of Phosphatidylcholine-Specific Phospholipase C in Breast and Ovarian Cancer: Impact on MRS-Detected Choline Metabolic Profile and Perspectives for Targeted TherapyOrdering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis.Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier.Signal transduction of stress via ceramide.Role of caspases in CD95-induced biphasic activation of acid sphingomyelinase.Different roles of protein kinase C alpha and delta isoforms in the regulation of neutral sphingomyelinase activity in HL-60 cellsCeramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells.In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: relevance to Alzheimer's disease and other oxApoptosis is associated with triacylglycerol accumulation in Jurkat T-cells.The tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytesTumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced mitochondrial pathway to apoptosis and caspase activation is potentiated by phospholipid scramblase-3.Ceramide inhibits antigen uptake and presentation by dendritic cells.Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice.Apoptosis and apoptosis-associated perturbations of peripheral blood lymphocytes during HIV infection: comparison between AIDS patients and asymptomatic long-term non-progressors.
P2860
Q24319856-330C1986-9BD5-43B6-BAD1-A691941F30FBQ28344228-46C2842A-024A-4A72-B379-AA5488B8959AQ28360876-D2AA564A-FA81-43C8-AF45-0E9AB1D8FE8DQ33576337-E0485B70-1FDC-46C2-959B-0E75A674EC1AQ33699139-2B765506-AE33-46E4-B93E-D9588E63330FQ34086900-E533E403-2AED-45DF-A083-6FD443FA9A1DQ34139591-36CC1803-827B-437C-81F0-86BE6CD570FAQ34139596-A7C37D1D-5BD8-4430-A03B-E8E528F6C815Q35132088-DF419A4E-C559-4D3B-BE87-4FECAD76ED28Q36380942-46CEBEA5-C190-46FF-8452-069A383FF1A1Q36400469-EB91BE81-D5EB-41A2-A782-F6FAB07F9DBDQ36508125-E810F5D3-28FC-403B-91B5-88C4C946801CQ36654745-2097E6DE-6599-412A-AAF8-56B7973D921EQ36664164-A4D96259-B527-43D9-A695-2E759466DA33Q36992077-34A6BBA2-93B2-4C22-AA92-48D8EF10A4D3Q38021345-E970D63F-0EAF-451C-ABFC-B3D8FD085F0EQ40326382-178BC539-78A3-4AEC-BC29-1C1984220EBDQ40572969-B409812E-94E0-4AE5-B4B2-7C0B528C4025Q40850451-5DB1769F-AF17-49EB-A919-17D19AEA3E37Q40857896-0EBFBFAB-2638-4067-910E-274D5413A1EFQ41841345-6FB84AAA-E8C5-4563-9F4B-B1F75A98362EQ41893524-AE59C690-18FD-442F-BF7B-1B183FA3B787Q41897331-0B300D35-A2B3-4110-BEFD-01449BCA637DQ41944072-3A8414E1-DB7A-4689-A434-029DF99584A4Q42058202-43659A7D-5038-4544-B0FB-85A6F24E2218Q42225747-0C56D197-28FE-4997-97A7-A643363E62E1Q42321804-3B4726C0-3D64-4218-8138-DC146AF70415Q42425074-7B39C331-1989-40AF-9274-9885A94F8B03Q42948037-0AEB545D-82A2-43ED-806A-2A9C6B835C4FQ51020334-B15B8222-BA31-49FF-A647-3074D4305F05Q52541810-EA1698A0-EF14-4F95-9BC7-844CCAC0C599
P2860
Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1995
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Multiple pathways originate at ...... ation of the apoptotic signal.
@en
Multiple pathways originate at the Fas/APO-1
@nl
type
label
Multiple pathways originate at ...... ation of the apoptotic signal.
@en
Multiple pathways originate at the Fas/APO-1
@nl
prefLabel
Multiple pathways originate at ...... ation of the apoptotic signal.
@en
Multiple pathways originate at the Fas/APO-1
@nl
P2093
P2860
P1433
P1476
Multiple pathways originate at ...... gation of the apoptotic signal
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1995.TB00274.X
P407
P577
1995-12-01T00:00:00Z