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Defining the consequences of genetic variation on a proteome-wide scale.

Defining the consequences of genetic variation on a proteome-wide scale.

http://www.wikidata.org/entity/Q37625941

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A Golden Age for Working with Public Proteomics Data An Expanded View of Complex Traits: From Polygenic to Omnigenic Toward Personalized Gene Therapy: Characterizing the Host Genetic Control of Lentiviral-Vector-Mediated Hepatic Gene Delivery.Multi-omics approaches to disease.An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci Translational Rodent Models for Research on Parasitic Protozoa-A Review of Confounders and Possibilities Extensive Peptide Fractionation and y1 Ion-Based Interference Detection Method for Enabling Accurate Quantification by Isobaric Labeling and Mass Spectrometry.Genomes of the Mouse Collaborative Cross.Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice.Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling.Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity.Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection.Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers Of mice and CRISPR: The post-CRISPR future of the mouse as a model system for the human condition.Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.How mice are indispensable for understanding obesity and diabetes genetics.A Strategy to Combine Sample Multiplexing with Targeted Proteomics Assays for High-Throughput Protein Signature Characterization.Comparative transcriptomics in human and mouse.Untangling Genetic Risk for Alzheimer's Disease.Immunogenomic approaches to understand the function of immune disease variants.G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells The Evolutionary Fates of a Large Segmental Duplication in Mouse.Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes.Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer.A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events.Genetic background influences susceptibility to chemotherapy-induced hematotoxicity.Extensive Homeostatic T Cell Phenotypic Variation within the Collaborative Cross.Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator.Vitrification of Rhesus Macaque Mesenchymal Stem Cells and the Effects on Global Gene Expression.Single subject transcriptome analysis to identify functionally signed gene set or pathway activity.Integrated omics dissection of proteome dynamics during cardiac remodeling.Recent advances in proteomic profiling of pancreatic ductal adenocarcinoma and the road ahead.Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities.Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1.Selenium regulation of selenoprotein enzyme activity and transcripts in a pilot study with Founder strains from the Collaborative Cross.Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees.Molecular and functional signatures in a novel Alzheimer's disease mouse model assessed by quantitative proteomics.Initiating Events in Direct Cardiomyocyte Reprogramming.Hierarchical Analysis of RNA-Seq Reads Improves the Accuracy of Allele-specific Expression.

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Defining the consequences of genetic variation on a proteome-wide scale.

http://www.wikidata.org/entity/Q37625941

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 15 June 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Defining the consequences of genetic variation on a proteome-wide scale.

@en

Defining the consequences of genetic variation on a proteome-wide scale.

@nl

type

label

Defining the consequences of genetic variation on a proteome-wide scale.

@en

Defining the consequences of genetic variation on a proteome-wide scale.

@nl

prefLabel

Defining the consequences of genetic variation on a proteome-wide scale.

@en

Defining the consequences of genetic variation on a proteome-wide scale.

@nl

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Defining the consequences of genetic variation on a proteome-wide scale

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Daniel M Gatti

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Gary A Churchill

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Joel M Chick

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Karen L Svenson

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Petr Simecek

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Steven C Munger

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P2860

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10.1038/NATURE18270

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7608

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Narayanan Raghupathy

Edward L Huttlin

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2016-06-15T00:00:00Z

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27309819

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